Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosis of upper urinary tract urothelial carcinoma

Verfasser / Beitragende:
[Seiji Asai, Tetsuya Fukumoto, Nozomu Tanji, Noriyoshi Miura, Masao Miyagawa, Kenichi Nishimura, Yutaka Yanagihara, Akitomi Shirato, Yuki Miyauchi, Tadahiko Kikugawa, Masayoshi Yokoyama]
Ort, Verlag, Jahr:
2015
Enthalten in:
International Journal of Clinical Oncology, 20/5(2015-10-01), 1042-1047
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10147-015-0817-4  |2 doi 
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245 0 0 |a Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosis of upper urinary tract urothelial carcinoma  |h [Elektronische Daten]  |c [Seiji Asai, Tetsuya Fukumoto, Nozomu Tanji, Noriyoshi Miura, Masao Miyagawa, Kenichi Nishimura, Yutaka Yanagihara, Akitomi Shirato, Yuki Miyauchi, Tadahiko Kikugawa, Masayoshi Yokoyama] 
520 3 |a Background: The purpose of this study was to assess the ability of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to detect upper urinary tract urothelial carcinomas (UTUC) compared with pathological examination of tissues obtained by ureteroscopic biopsy and split cytologic analysis of urine obtained after retrograde pyelography. Methods: Clinicopathological records of patients at our institution were retrospectively reviewed. Fifty patients with clinically suspected UTUC, who were histologically diagnosed by nephroureterectomy, partial ureterectomy, or endoscopic biopsy, were included. The patient cohort included 42 men and 8 women, with a median age of 73 (range 54-92) years. Results: Only 27% of 49 patients with UTUC had positive voided urine cytology, and 33% of 40 patients had positive split urine cytology. In addition, 40% of 10 patients had a positive endoscopic biopsy. However, 83% of 48 patients with UTUC had positive results from FDG-PET/CT examination. The positive predictive value of FDG-PET/CT was 95%. There were no correlations between sensitivity and tumor stage or tumor grade. Sensitivity of FDG-PET/CT for patients with and without diabetes mellitus was 60 and 89%, respectively. Conclusions: These preliminary results from a small number of patients revealed that FDG-PET/CT enabled effective detection of UTUC. 
540 |a Japan Society of Clinical Oncology, 2015 
690 7 |a FDG-PET/CT  |2 nationallicence 
690 7 |a Upper urinary tract urothelial carcinoma  |2 nationallicence 
690 7 |a Urine cytology  |2 nationallicence 
690 7 |a Ureteroscopy  |2 nationallicence 
700 1 |a Asai  |D Seiji  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Fukumoto  |D Tetsuya  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Tanji  |D Nozomu  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Miura  |D Noriyoshi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Miyagawa  |D Masao  |u Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Nishimura  |D Kenichi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Yanagihara  |D Yutaka  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Shirato  |D Akitomi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Miyauchi  |D Yuki  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Kikugawa  |D Tadahiko  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
700 1 |a Yokoyama  |D Masayoshi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
773 0 |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/5(2015-10-01), 1042-1047  |x 1341-9625  |q 20:5<1042  |1 2015  |2 20  |o 10147 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Asai  |D Seiji  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fukumoto  |D Tetsuya  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tanji  |D Nozomu  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miura  |D Noriyoshi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miyagawa  |D Masao  |u Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nishimura  |D Kenichi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yanagihara  |D Yutaka  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shirato  |D Akitomi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miyauchi  |D Yuki  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kikugawa  |D Tadahiko  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yokoyama  |D Masayoshi  |u Department of Urology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/5(2015-10-01), 1042-1047  |x 1341-9625  |q 20:5<1042  |1 2015  |2 20  |o 10147