Administration of chemotherapy via the median cubital vein without implantable central venous access ports: port-free chemotherapy for metastatic colorectal cancer patients

Verfasser / Beitragende:
[Yoichiro Yoshida, Seiichiro Hoshino, Naoya Aisu, Masayasu Naito, Syu Tanimura, Ai Mogi, Toshihiro Tanaka, Keiji Hirata, Kazuo Tamura, Yuichi Yamashita]
Ort, Verlag, Jahr:
2015
Enthalten in:
International Journal of Clinical Oncology, 20/2(2015-04-01), 332-337
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10147-014-0703-5  |2 doi 
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245 0 0 |a Administration of chemotherapy via the median cubital vein without implantable central venous access ports: port-free chemotherapy for metastatic colorectal cancer patients  |h [Elektronische Daten]  |c [Yoichiro Yoshida, Seiichiro Hoshino, Naoya Aisu, Masayasu Naito, Syu Tanimura, Ai Mogi, Toshihiro Tanaka, Keiji Hirata, Kazuo Tamura, Yuichi Yamashita] 
520 3 |a Background: Repeated venous punctures are usually required during chemotherapy administration for cancer patients. Central venous catheters and implantable port systems have substantially facilitated vascular access, and safe, easy-to-handle port systems have become an integral part of daily clinical routines in oncology. However, several serious complications are associated with central venous ports (CV-ports), and recent developments of combined oral capecitabine and oxaliplatin (XELOX) therapies allow CV-port-free administration. In this study, the safety and efficacy of CV-port-free chemotherapy administration via the median cubital vein was assessed in metastatic colorectal cancer patients. Methods: This study included 144 patients who received XELOX+bevacizumab (BV) or XELOX therapy for metastatic colorectal cancer without CV-port implantation. Results: Eighty-five patients experienced transient vascular pain. The drip infusion route was switched to the opposite side following vascular pain in only 1 patient. No patients required CV-port implantation or delayed treatment due to adverse events associated with drug administration via the peripheral vein. Grade 3 or higher hemotoxicity and grade 3 or higher non-hematological toxicity was noted in 12.5 and 17.4% of patients, respectively. Conclusions: Port-free-chemotherapy administration via the median cubital vein is appropriate for patients with colorectal cancer, thereby avoiding complications associated with CV-ports. 
540 |a Japan Society of Clinical Oncology, 2014 
690 7 |a Chemotherapy  |2 nationallicence 
690 7 |a Colorectal cancer  |2 nationallicence 
690 7 |a Central venous port  |2 nationallicence 
690 7 |a Median cubital vein  |2 nationallicence 
700 1 |a Yoshida  |D Yoichiro  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
700 1 |a Hoshino  |D Seiichiro  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
700 1 |a Aisu  |D Naoya  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
700 1 |a Naito  |D Masayasu  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
700 1 |a Tanimura  |D Syu  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
700 1 |a Mogi  |D Ai  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
700 1 |a Tanaka  |D Toshihiro  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
700 1 |a Hirata  |D Keiji  |u Department of Surgery, Fukuoka Sanno Hospital, Fukuoka, Japan  |4 aut 
700 1 |a Tamura  |D Kazuo  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
700 1 |a Yamashita  |D Yuichi  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yoshida  |D Yoichiro  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hoshino  |D Seiichiro  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aisu  |D Naoya  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Naito  |D Masayasu  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tanimura  |D Syu  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mogi  |D Ai  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tanaka  |D Toshihiro  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hirata  |D Keiji  |u Department of Surgery, Fukuoka Sanno Hospital, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tamura  |D Kazuo  |u Division of Oncology, Hematology and Infectious Diseases, Department of Internal Medicine, Fukuoka University Faculty of Medicine, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yamashita  |D Yuichi  |u Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, 7-45-1 Nanakuma, Jonan-ku, 814-0180, Fukuoka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t International Journal of Clinical Oncology  |d Springer Japan  |g 20/2(2015-04-01), 332-337  |x 1341-9625  |q 20:2<332  |1 2015  |2 20  |o 10147