Alveolar echinococcosis: correlation between hepatic MRI findings and FDG-PET/CT metabolic activity

Verfasser / Beitragende:
[Amel Azizi, Oleg Blagosklonov, Ahmed Lounis, Louis Berthet, Dominique-Angèle Vuitton, Solange Bresson-Hadni, Eric Delabrousse]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/1(2015-01-01), 56-63
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0183-0  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0183-0 
245 0 0 |a Alveolar echinococcosis: correlation between hepatic MRI findings and FDG-PET/CT metabolic activity  |h [Elektronische Daten]  |c [Amel Azizi, Oleg Blagosklonov, Ahmed Lounis, Louis Berthet, Dominique-Angèle Vuitton, Solange Bresson-Hadni, Eric Delabrousse] 
520 3 |a Objective: To correlate the appearance of alveolar echinococcosis (AE) hepatic lesions in magnetic resonance imaging (MRI) as defined by Kodama, to the metabolic activity visualized in 18-fluoro-deoxyglucose positron emission tomography combined with computed tomography (PET/CT). Materials and methods: Forty-two patients diagnosed with AE and who underwent both MRI and PET/CT were included. The forty-two hepatic lesions were divided into five types according to Kodama's classification by three independent readers blinded with regard to the PET/CT information. Concerning PET/CT, two independent readers, unaware of the MRI information, considered the results as positive when an increased FDG-uptake was observed at 1 or 3h after FDG-injection, and as negative when no increased uptake was noted. Inter-observer agreement was assessed by using κ statistics. Results: Forty-two lesions were counted and the mean diameter of overall evaluated lesions was 6.3cm. One lesion (2.4%) was categorized as type 1, 11 (26.2%) as type 2, 24 (57.1%) as type 3, 3 (7.1%) as type 4, and 3 (7.1%) as type 5. The inter-observer analysis found a κ coefficient of 0.96. All type-1, 90.9% of type-2 and 87.5% of type-3 lesions showed an increased FDG-uptake on PET/CT images. All non-microcystic AE liver lesions (types 4 and 5) showed no abnormal increased FDG-uptake on PET/CT images. The inter-observer analysis at 1 and 3h found a κ coefficient of 0.95 and 0.92, respectively. Conclusions: In patients with AE liver lesions, the absence of microcysts on MRI is strongly correlated to a metabolically inactive disease. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Alveolar echinococcosis  |2 nationallicence 
690 7 |a Liver  |2 nationallicence 
690 7 |a MRI  |2 nationallicence 
690 7 |a FDG-PET/CT  |2 nationallicence 
690 7 |a Metabolic activity  |2 nationallicence 
700 1 |a Azizi  |D Amel  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
700 1 |a Blagosklonov  |D Oleg  |u Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
700 1 |a Lounis  |D Ahmed  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
700 1 |a Berthet  |D Louis  |u Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
700 1 |a Vuitton  |D Dominique-Angèle  |u WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France  |4 aut 
700 1 |a Bresson-Hadni  |D Solange  |u WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France  |4 aut 
700 1 |a Delabrousse  |D Eric  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 56-63  |x 0942-8925  |q 40:1<56  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0183-0  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0183-0  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Azizi  |D Amel  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Blagosklonov  |D Oleg  |u Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lounis  |D Ahmed  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Berthet  |D Louis  |u Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Vuitton  |D Dominique-Angèle  |u WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bresson-Hadni  |D Solange  |u WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Delabrousse  |D Eric  |u Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 56-63  |x 0942-8925  |q 40:1<56  |1 2015  |2 40  |o 261