caa a22 4500 605491925 CHVBK 20210128100512.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00261-014-0183-0 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0183-0 Alveolar echinococcosis: correlation between hepatic MRI findings and FDG-PET/CT metabolic activity [Elektronische Daten] [Amel Azizi, Oleg Blagosklonov, Ahmed Lounis, Louis Berthet, Dominique-Angèle Vuitton, Solange Bresson-Hadni, Eric Delabrousse] Objective: To correlate the appearance of alveolar echinococcosis (AE) hepatic lesions in magnetic resonance imaging (MRI) as defined by Kodama, to the metabolic activity visualized in 18-fluoro-deoxyglucose positron emission tomography combined with computed tomography (PET/CT). Materials and methods: Forty-two patients diagnosed with AE and who underwent both MRI and PET/CT were included. The forty-two hepatic lesions were divided into five types according to Kodama's classification by three independent readers blinded with regard to the PET/CT information. Concerning PET/CT, two independent readers, unaware of the MRI information, considered the results as positive when an increased FDG-uptake was observed at 1 or 3h after FDG-injection, and as negative when no increased uptake was noted. Inter-observer agreement was assessed by using κ statistics. Results: Forty-two lesions were counted and the mean diameter of overall evaluated lesions was 6.3cm. One lesion (2.4%) was categorized as type 1, 11 (26.2%) as type 2, 24 (57.1%) as type 3, 3 (7.1%) as type 4, and 3 (7.1%) as type 5. The inter-observer analysis found a κ coefficient of 0.96. All type-1, 90.9% of type-2 and 87.5% of type-3 lesions showed an increased FDG-uptake on PET/CT images. All non-microcystic AE liver lesions (types 4 and 5) showed no abnormal increased FDG-uptake on PET/CT images. The inter-observer analysis at 1 and 3h found a κ coefficient of 0.95 and 0.92, respectively. Conclusions: In patients with AE liver lesions, the absence of microcysts on MRI is strongly correlated to a metabolically inactive disease. Springer Science+Business Media New York, 2014 Alveolar echinococcosis nationallicence Liver nationallicence MRI nationallicence FDG-PET/CT nationallicence Metabolic activity nationallicence Azizi Amel Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut Blagosklonov Oleg Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut Lounis Ahmed Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut Berthet Louis Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut Vuitton Dominique-Angèle WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France aut Bresson-Hadni Solange WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France aut Delabrousse Eric Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 56-63 0942-8925 40:1<56 2015 40 261 https://doi.org/10.1007/s00261-014-0183-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0183-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Azizi Amel Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut NATIONALLICENCE 700 1- Blagosklonov Oleg Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut NATIONALLICENCE 700 1- Lounis Ahmed Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut NATIONALLICENCE 700 1- Berthet Louis Departmentof Nuclear Medicine, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut NATIONALLICENCE 700 1- Vuitton Dominique-Angèle WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France aut NATIONALLICENCE 700 1- Bresson-Hadni Solange WHO Collaborating Centre for Prevention and Treatment of Human Echinococcosis, Besançon, France aut NATIONALLICENCE 700 1- Delabrousse Eric Department of Radiology, University Hospital, 3 Boulevard Fleming, 25030, Besançon, France aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 56-63 0942-8925 40:1<56 2015 40 261