Differentiation of poorly differentiated colorectal adenocarcinomas from well- or moderately differentiated colorectal adenocarcinomas at contrast-enhanced multidetector CT

Verfasser / Beitragende:
[Ji Kim, Jeong Lee, Jee Baek, Sung Moon, Se Kim, Joon Han, Byung Choi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/1(2015-01-01), 1-10
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0176-z  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0176-z 
245 0 0 |a Differentiation of poorly differentiated colorectal adenocarcinomas from well- or moderately differentiated colorectal adenocarcinomas at contrast-enhanced multidetector CT  |h [Elektronische Daten]  |c [Ji Kim, Jeong Lee, Jee Baek, Sung Moon, Se Kim, Joon Han, Byung Choi] 
520 3 |a Purpose: The purpose of the study is to describe the CT findings of poorly differentiated (PD) colorectal adenocarcinoma (CRAC) compared with those of well- (WD) or moderately differentiated (MD) CRAC. Materials and methods: One hundred and thirteen patients with pathologically proven PD (n=26), WD (n=35), or MD (n=52) CRACs and who had undergone preoperative, contrast-enhanced multidetector CT (MDCT) imaging were included. Analysis of the CT findings included the morphologic and enhancement features of primary tumors and regional lymph nodes (LNs), and the presence of direct invasion, colonic obstruction, and distant metastasis. The significance of these findings was determined using the χ 2 test. Results: Significant features favoring the diagnosis of PD CRACs over WD or MD CRACs included their bulky shape, heterogeneous enhancement, iso- or hypoattenuation compared with that of muscle, nodular pericolic fat infiltration, regional LNs>10mm, and/or with iso- or hypoattenuation compared with that of muscle, and the presence of distant metastasis (P<0.05). When at least two of these seven imaging features were used in combination, the sensitivity and specificity in the diagnosis of PD CRACs were 88% and 70%, respectively. Conclusion: Using characteristic CT features, one can differentiate PD CRAC from WD or MD CRAC with a high degree of accuracy on contrast-enhanced MDCT. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Poorly differentiated (PD)  |2 nationallicence 
690 7 |a Colorectal adenocarcinoma (CRAC)  |2 nationallicence 
690 7 |a Multidetector CT (MDCT)  |2 nationallicence 
700 1 |a Kim  |D Ji  |u Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea  |4 aut 
700 1 |a Lee  |D Jeong  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Baek  |D Jee  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Moon  |D Sung  |u Department of Radiology, Kyung Hee University College of Medicine, Seoul, Korea  |4 aut 
700 1 |a Kim  |D Se  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Han  |D Joon  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Choi  |D Byung  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 1-10  |x 0942-8925  |q 40:1<1  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0176-z  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Ji  |u Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Jeong  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Baek  |D Jee  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Moon  |D Sung  |u Department of Radiology, Kyung Hee University College of Medicine, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Se  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Han  |D Joon  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Byung  |u Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 1-10  |x 0942-8925  |q 40:1<1  |1 2015  |2 40  |o 261