caa a22 4500 605491941 CHVBK 20210128100512.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00261-014-0176-z doi (NATIONALLICENCE)springer-10.1007/s00261-014-0176-z Differentiation of poorly differentiated colorectal adenocarcinomas from well- or moderately differentiated colorectal adenocarcinomas at contrast-enhanced multidetector CT [Elektronische Daten] [Ji Kim, Jeong Lee, Jee Baek, Sung Moon, Se Kim, Joon Han, Byung Choi] Purpose: The purpose of the study is to describe the CT findings of poorly differentiated (PD) colorectal adenocarcinoma (CRAC) compared with those of well- (WD) or moderately differentiated (MD) CRAC. Materials and methods: One hundred and thirteen patients with pathologically proven PD (n=26), WD (n=35), or MD (n=52) CRACs and who had undergone preoperative, contrast-enhanced multidetector CT (MDCT) imaging were included. Analysis of the CT findings included the morphologic and enhancement features of primary tumors and regional lymph nodes (LNs), and the presence of direct invasion, colonic obstruction, and distant metastasis. The significance of these findings was determined using the χ 2 test. Results: Significant features favoring the diagnosis of PD CRACs over WD or MD CRACs included their bulky shape, heterogeneous enhancement, iso- or hypoattenuation compared with that of muscle, nodular pericolic fat infiltration, regional LNs>10mm, and/or with iso- or hypoattenuation compared with that of muscle, and the presence of distant metastasis (P<0.05). When at least two of these seven imaging features were used in combination, the sensitivity and specificity in the diagnosis of PD CRACs were 88% and 70%, respectively. Conclusion: Using characteristic CT features, one can differentiate PD CRAC from WD or MD CRAC with a high degree of accuracy on contrast-enhanced MDCT. Springer Science+Business Media New York, 2014 Poorly differentiated (PD) nationallicence Colorectal adenocarcinoma (CRAC) nationallicence Multidetector CT (MDCT) nationallicence Kim Ji Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea aut Lee Jeong Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut Baek Jee Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut Moon Sung Department of Radiology, Kyung Hee University College of Medicine, Seoul, Korea aut Kim Se Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut Han Joon Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut Choi Byung Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 1-10 0942-8925 40:1<1 2015 40 261 https://doi.org/10.1007/s00261-014-0176-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0176-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Ji Department of Radiology, Gyeongsang National University School of Medicine, Jinju, Korea aut NATIONALLICENCE 700 1- Lee Jeong Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut NATIONALLICENCE 700 1- Baek Jee Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut NATIONALLICENCE 700 1- Moon Sung Department of Radiology, Kyung Hee University College of Medicine, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Se Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut NATIONALLICENCE 700 1- Han Joon Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut NATIONALLICENCE 700 1- Choi Byung Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744, Seoul, Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 1-10 0942-8925 40:1<1 2015 40 261