MRI for differentiation of renal cell carcinoma with sarcomatoid component from other renal tumor types

Verfasser / Beitragende:
[Mitsuru Takeuchi, Tatsuya Kawai, Tomohiro Suzuki, Taku Naiki, Noriyasu Kawai, Yukio Fujiyoshi, Hiroshi Inagaki, Kenjiro Kohri, Masaki Hara, Yuta Shibamoto]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/1(2015-01-01), 112-119
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0185-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0185-y 
245 0 0 |a MRI for differentiation of renal cell carcinoma with sarcomatoid component from other renal tumor types  |h [Elektronische Daten]  |c [Mitsuru Takeuchi, Tatsuya Kawai, Tomohiro Suzuki, Taku Naiki, Noriyasu Kawai, Yukio Fujiyoshi, Hiroshi Inagaki, Kenjiro Kohri, Masaki Hara, Yuta Shibamoto] 
520 3 |a Purpose: To investigate the usefulness of MRI for detection of sarcomatoid renal cell carcinoma (SRCC) components within RCC and differentiation from other renal tumors. Methods: Two observers independently interpreted T2-weighted images of 10 patients with pathologically confirmed RCCs with SRCC and 131 with non-SRCC renal tumors, with special reference to conspicuously low signal intensity (SI) areas (T2LIA) compared to the renal cortex. SRCC probability was classified as (1) definitely non-SRCC, no T2LIA; (2) probably non-SRCC, <1cm T2LIA; (3) low probability of SRCC, homogeneous tumor with 1-3cm T2LIA; (4) probably SRCC, heterogeneous tumor with 1-3cm T2LIA; and (5) definitely SRCC, >3cm T2LIA, multiple >1cm T2LIAs, or showing disruption of the pseudocapsule. The observers used chemical shift imaging to exclude the area representing hemorrhage or hemosiderin deposition from T2LIA. Scores of 4/5 were regarded as positive for evaluating the accuracy and area under the receiver operating characteristic curve. The SI ratio of the lowest SI in the tumor to that of the renal cortex in the 1 and ≥2 score groups was compared using Mann-Whitney's U test. Results: Sensitivity, specificity, accuracy, and positive and negative predictive values were 90%, 95%, 94%, 56%, and 99%, respectively, and area under the receiver operating characteristic curve was 0.93. The mean SI ratio of the lowest SI in the tumor to that of the renal cortex was significantly lower in the ≥2 score group (0.58) than in the 1 score group (1.36). Conclusions: MRI predicted RCC with SRCC with a moderate positive predictive value and a high negative predictive value. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Carcinoma  |2 nationallicence 
690 7 |a Renal Cell  |2 nationallicence 
690 7 |a Sarcomatoid renal cell carcinoma  |2 nationallicence 
690 7 |a Magnetic resonance imaging  |2 nationallicence 
690 7 |a T2-weighted imaging  |2 nationallicence 
690 7 |a Diagnosis  |2 nationallicence 
690 7 |a Differential  |2 nationallicence 
700 1 |a Takeuchi  |D Mitsuru  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Kawai  |D Tatsuya  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Suzuki  |D Tomohiro  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Naiki  |D Taku  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Kawai  |D Noriyasu  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Fujiyoshi  |D Yukio  |u Department of Clinical Pathology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Inagaki  |D Hiroshi  |u Department of Clinical Pathology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Kohri  |D Kenjiro  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
700 1 |a Hara  |D Masaki  |u Department of Radiology, Nagoya City West Medical Center, 1-1-1, hirade-cho, kita-ku, 462-8508, Nagoya, Japan  |4 aut 
700 1 |a Shibamoto  |D Yuta  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 112-119  |x 0942-8925  |q 40:1<112  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0185-y  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0185-y  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takeuchi  |D Mitsuru  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kawai  |D Tatsuya  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Suzuki  |D Tomohiro  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Naiki  |D Taku  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kawai  |D Noriyasu  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fujiyoshi  |D Yukio  |u Department of Clinical Pathology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Inagaki  |D Hiroshi  |u Department of Clinical Pathology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kohri  |D Kenjiro  |u Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hara  |D Masaki  |u Department of Radiology, Nagoya City West Medical Center, 1-1-1, hirade-cho, kita-ku, 462-8508, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shibamoto  |D Yuta  |u Department of Radiology, Nagoya City University Graduate School of Medical Sciences and Medical school, 1 Kawasumi Mizuho-cho, Mizuho-ku, 467-8601, Nagoya, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 112-119  |x 0942-8925  |q 40:1<112  |1 2015  |2 40  |o 261