caa a22 4500 605492115 CHVBK 20210128100513.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00261-014-0201-2 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0201-2 Comparative evaluation of three-dimensional Gd-EOB-DTPA-enhanced MR fusion imaging with CT fusion imaging in the assessment of treatment effect of radiofrequency ablation of hepatocellular carcinoma [Elektronische Daten] [Yuki Makino, Yasuharu Imai, Takumi Igura, Masatoshi Hori, Kazuto Fukuda, Yoshiyuki Sawai, Sachiyo Kogita, Norihiko Fujita, Tetsuo Takehara, Takamichi Murakami] Purpose: To assess the feasibility of fusion of pre- and post-ablation gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI) to evaluate the effects of radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC), compared with similarly fused CT images Patients and methods: This retrospective study included 67 patients with 92 HCCs treated with RFA. Fusion images of pre- and post-RFA dynamic CT, and pre- and post-RFA Gd-EOB-DTPA-MRI were created, using a rigid registration method. The minimal ablative margin measured on fusion imaging was categorized into three groups: (1) tumor protruding outside the ablation zone boundary, (2) ablative margin 0-<5.0mm beyond the tumor boundary, and (3) ablative margin ≥5.0mm beyond the tumor boundary. The categorization of minimal ablative margins was compared between CT and MR fusion images. Results: In 57 (62.0%) HCCs, treatment evaluation was possible both on CT and MR fusion images, and the overall agreement between them for the categorization of minimal ablative margin was good (κ coefficient=0.676, P<0.01). MR fusion imaging enabled treatment evaluation in a significantly larger number of HCCs than CT fusion imaging (86/92 [93.5%] vs. 62/92 [67.4%], P<0.05). Conclusions: Fusion of pre- and post-ablation Gd-EOB-DTPA-MRI is feasible for treatment evaluation after RFA. It may enable accurate treatment evaluation in cases where CT fusion imaging is not helpful. Springer Science+Business Media New York, 2014 Hepatocellular carcinoma nationallicence Radiofrequency ablation nationallicence Fusion imaging nationallicence Ablative margin nationallicence Gd-EOB-DTPA nationallicence Makino Yuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Imai Yasuharu Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Igura Takumi Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Hori Masatoshi Department of Radiology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut Fukuda Kazuto Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Sawai Yoshiyuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Kogita Sachiyo Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Fujita Norihiko Department of Radiology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut Takehara Tetsuo Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut Murakami Takamichi Department of Radiology, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, 589-8511, Osaka-sayama, Osaka, Japan aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 102-111 0942-8925 40:1<102 2015 40 261 https://doi.org/10.1007/s00261-014-0201-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0201-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Makino Yuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Imai Yasuharu Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Igura Takumi Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Hori Masatoshi Department of Radiology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Fukuda Kazuto Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Sawai Yoshiyuki Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Kogita Sachiyo Department of Gastroenterology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Fujita Norihiko Department of Radiology, Ikeda Municipal Hospital, 3-1-18, Johnan, 563-8510, Ikeda, Osaka, Japan aut NATIONALLICENCE 700 1- Takehara Tetsuo Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, 565-0871, Suita, Osaka, Japan aut NATIONALLICENCE 700 1- Murakami Takamichi Department of Radiology, Kinki University Faculty of Medicine, 377-2, Ohnohigashi, 589-8511, Osaka-sayama, Osaka, Japan aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/1(2015-01-01), 102-111 0942-8925 40:1<102 2015 40 261