Pancreatic adenocarcinoma: MRI conspicuity and pathologic correlations
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| 003 | CHVBK | ||
| 005 | 20210128100513.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150101xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00261-014-0196-8 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-014-0196-8 | ||
| 245 | 0 | 0 | |a Pancreatic adenocarcinoma: MRI conspicuity and pathologic correlations |h [Elektronische Daten] |c [Laurence Legrand, Véronique Duchatelle, Vincent Molinié, Isabelle Boulay-Coletta, Elodie Sibileau, Marc Zins] |
| 520 | 3 | |a Purpose: To identify the MRI sequences producing the greatest pancreatic adenocarcinoma conspicuity and to assess correlations linking MRI signal intensity and apparent diffusion coefficient to histopathological findings. Methods: We retrospectively included 22 patients with pancreatic adenocarcinoma who underwent MRI (1.5 or 3T) before surgical resection. Fat-suppressed (FS) T1- and T2-weighted sequences; 3D FS dynamic T1-weighted gadolinium-enhanced gradient-echo (GRE) imaging at the arterial, portal, and delayed phases; and diffusion-weighted imaging (DWI) with b values of 600-800s/mm2 were reviewed. On each sequence, we assessed tumor conspicuity both qualitatively (3-point scale) and quantitatively (tumor-to-proximal and -distal pancreas contrast ratios), and we performed paired Wilcoxon tests to compare these data across sequences. We evaluated correlations between histopathological characteristics and MRI features. Results: 21/22 (95%) tumors were hypointense by 3D FS T1 GRE arterial phase imaging, which produced the greatest tumor conspicuity (p≤0.02). By DWI, 5/20 (25%) of tumors were isointense. The correlation between size by histology and MRI was strongest with DWI. A progressive enhancement pattern was associated with extensive and dense fibrous stroma (p≤0.03). Conclusions: 3D FS T1 GRE arterial phase imaging produces greater pancreatic adenocarcinoma conspicuity compared to DWI but underestimates tumor size. DWI provides the best size evaluation but fails to delineate the tumor in one-fourth of cases. | |
| 540 | |a Springer Science+Business Media New York, 2014 | ||
| 690 | 7 | |a Pancreas |2 nationallicence | |
| 690 | 7 | |a Adenocarcinoma |2 nationallicence | |
| 690 | 7 | |a Magnetic resonance imaging |2 nationallicence | |
| 690 | 7 | |a Diffusion-weighted imaging |2 nationallicence | |
| 690 | 7 | |a Pathology |2 nationallicence | |
| 690 | 7 | |a ADC : Apparent diffusion coefficient |2 nationallicence | |
| 690 | 7 | |a DWI : Diffusion-weighted imaging |2 nationallicence | |
| 690 | 7 | |a FRFSE : Fast-recovery fast spin echo |2 nationallicence | |
| 690 | 7 | |a FS : Fat-suppressed |2 nationallicence | |
| 690 | 7 | |a GRE : Gradient echo |2 nationallicence | |
| 690 | 7 | |a ROI : Region of interest |2 nationallicence | |
| 690 | 7 | |a SI : Signal intensity |2 nationallicence | |
| 700 | 1 | |a Legrand |D Laurence |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 700 | 1 | |a Duchatelle |D Véronique |u Pathology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 700 | 1 | |a Molinié |D Vincent |u Pathology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 700 | 1 | |a Boulay-Coletta |D Isabelle |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 700 | 1 | |a Sibileau |D Elodie |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 700 | 1 | |a Zins |D Marc |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/1(2015-01-01), 85-94 |x 0942-8925 |q 40:1<85 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-014-0196-8 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-014-0196-8 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Legrand |D Laurence |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Duchatelle |D Véronique |u Pathology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Molinié |D Vincent |u Pathology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Boulay-Coletta |D Isabelle |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sibileau |D Elodie |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zins |D Marc |u Radiology Department, Fondation Hôpital Saint-Joseph, 185 rue Raymond Losserand, 75014, Paris, France |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/1(2015-01-01), 85-94 |x 0942-8925 |q 40:1<85 |1 2015 |2 40 |o 261 | ||