Automated volumetric analysis for comparison of oral sulfate solution (SUPREP) with established cathartic agents at CT colonography

Verfasser / Beitragende:
[Peter Bannas, Joshua Bakke, James Patrick, Perry Pickhardt]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/1(2015-01-01), 11-18
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0186-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0186-x 
245 0 0 |a Automated volumetric analysis for comparison of oral sulfate solution (SUPREP) with established cathartic agents at CT colonography  |h [Elektronische Daten]  |c [Peter Bannas, Joshua Bakke, James Patrick, Perry Pickhardt] 
520 3 |a Purpose: To objectively compare residual colonic fluid volume and attenuation of oral sulfate solution (OSS) with four different established cathartic regimens using an automated volumetric software tool at CT colonography (CTC). Methods: This HIPAA-compliant study had institutional review board approval. Volumetric analysis of residual contrast-tagged colonic fluid was performed on CTC studies in 263 adults (mean age 60.1years; 137M/126F) using an automated volumetric software tool. Twenty-three patients receiving 177mL OSS (SUPREP; single-bottle purgation) were compared with 60 patients each receiving 45mL sodium phosphate (NaP), 90mL NaP (2× NaP), 592mL (two bottles) magnesium citrate (MgC), and 4,000mL polyethylene glycol (PEG). All patients received oral contrast cleansing after catharsis. Data were analyzed with unpaired t test with Welch correction and F test. Results: The mean volume of residual colonic fluid was less with OSS (125±60mL) than for established cathartic agents: 2× NaP (206±125mL, P<0.0001), MgC (184±125mL, P<0.01), PEG (166±114mL, P<0.05), and NaP (165±135mL, P=0.067). Variance of volumes was also significantly lower for OSS (range 28-251mL) than for established agents (range 4-853mL) (all P<0.01). Mean fluid attenuation was higher with OSS (956±168HU) than for established agents (all P<0.05): 2× NaP (455±191HU), MgC (691±154HU), NaP (779±127HU), and PEG (843±193HU). Conclusions: Automated volumetry allows rapid objective assessment of bowel preparation quality at CTC. Purgation with the novel oral sulfate solution (SUPREP) consistently resulted in less residual colonic fluid and higher fluid attenuation compared with established cathartic regimens. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Bowel preparation  |2 nationallicence 
690 7 |a CT colonography  |2 nationallicence 
690 7 |a Oral sulfate solution  |2 nationallicence 
690 7 |a Automated volumetry  |2 nationallicence 
700 1 |a Bannas  |D Peter  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
700 1 |a Bakke  |D Joshua  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
700 1 |a Patrick  |D James  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
700 1 |a Pickhardt  |D Perry  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 11-18  |x 0942-8925  |q 40:1<11  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0186-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0186-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bannas  |D Peter  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bakke  |D Joshua  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Patrick  |D James  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pickhardt  |D Perry  |u Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., 53792-3252, Madison, WI, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/1(2015-01-01), 11-18  |x 0942-8925  |q 40:1<11  |1 2015  |2 40  |o 261