68Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer

Verfasser / Beitragende:
[Matthias Eiber, Stephan Nekolla, Tobias Maurer, Gregor Weirich, Hans-Jürgen Wester, Markus Schwaiger]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/6(2015-08-01), 1769-1771
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0301-z  |2 doi 
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245 0 0 |a 68Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer  |h [Elektronische Daten]  |c [Matthias Eiber, Stephan Nekolla, Tobias Maurer, Gregor Weirich, Hans-Jürgen Wester, Markus Schwaiger] 
520 3 |a Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a 68Gallium-labeled ligand of the prostate-specific membrane antigen (68Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric 68Ga-PSMA PET/MR by combining molecular and structural information. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Prostate cancer  |2 nationallicence 
690 7 |a PET/MR  |2 nationallicence 
690 7 |a Multiparametric analysis  |2 nationallicence 
690 7 |a 68Ga-PSMA  |2 nationallicence 
690 7 |a Tumor biology  |2 nationallicence 
700 1 |a Eiber  |D Matthias  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
700 1 |a Nekolla  |D Stephan  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
700 1 |a Maurer  |D Tobias  |u Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
700 1 |a Weirich  |D Gregor  |u Department of Pathology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
700 1 |a Wester  |D Hans-Jürgen  |u Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany  |4 aut 
700 1 |a Schwaiger  |D Markus  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1769-1771  |x 0942-8925  |q 40:6<1769  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0301-z  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0301-z  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Eiber  |D Matthias  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nekolla  |D Stephan  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Maurer  |D Tobias  |u Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Weirich  |D Gregor  |u Department of Pathology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Wester  |D Hans-Jürgen  |u Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Schwaiger  |D Markus  |u Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1769-1771  |x 0942-8925  |q 40:6<1769  |1 2015  |2 40  |o 261