caa a22 4500 605492239 CHVBK 20210128100514.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-014-0301-z doi (NATIONALLICENCE)springer-10.1007/s00261-014-0301-z 68Ga-PSMA PET/MR with multimodality image analysis for primary prostate cancer [Elektronische Daten] [Matthias Eiber, Stephan Nekolla, Tobias Maurer, Gregor Weirich, Hans-Jürgen Wester, Markus Schwaiger] Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a 68Gallium-labeled ligand of the prostate-specific membrane antigen (68Ga-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric 68Ga-PSMA PET/MR by combining molecular and structural information. Springer Science+Business Media New York, 2014 Prostate cancer nationallicence PET/MR nationallicence Multiparametric analysis nationallicence 68Ga-PSMA nationallicence Tumor biology nationallicence Eiber Matthias Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut Nekolla Stephan Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut Maurer Tobias Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut Weirich Gregor Department of Pathology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut Wester Hans-Jürgen Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany aut Schwaiger Markus Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1769-1771 0942-8925 40:6<1769 2015 40 261 https://doi.org/10.1007/s00261-014-0301-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0301-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eiber Matthias Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Nekolla Stephan Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Maurer Tobias Department of Urology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Weirich Gregor Department of Pathology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 700 1- Wester Hans-Jürgen Pharmaceutical Radiochemistry, Technische Universität München, Garching, Germany aut NATIONALLICENCE 700 1- Schwaiger Markus Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1769-1771 0942-8925 40:6<1769 2015 40 261