Ablation therapy of hepatocellular carcinoma: a comparative study between radiofrequency and microwave ablation
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| 024 | 7 | 0 | |a 10.1007/s00261-015-0355-6 |2 doi |
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| 245 | 0 | 0 | |a Ablation therapy of hepatocellular carcinoma: a comparative study between radiofrequency and microwave ablation |h [Elektronische Daten] |c [Thomas Vogl, Parviz Farshid, Nagy Naguib, Stefan Zangos, Boris Bodelle, Jijo Paul, Emannuel Mbalisike, Martin Beeres, Nour-Eldin Nour-Eldin] |
| 520 | 3 | |a Purpose: The aim of the study is to retrospectively evaluate and compare the therapeutic response of Radiofrequency (RF) and Microwave (MW) ablation therapy of hepatocellular carcinoma (HCC). Materials and Methods: 53 consecutive patients (42 males, 11 females; mean age 59years, range: 40-68, SD: 4.2) underwent CT-guided percutaneous RF and MW ablation of 68 HCC liver lesions. The morphologic tumor response (number, location and size) was evaluated by magnetic resonance imaging. The follow-up protocol was 24h post-ablation then within 3 monthly intervals post-ablation in the first year and 6 monthly intervals thereafter. Results: Complete therapeutic response was noted in 84.4% (27/32) of lesions treated with RFA and in 88.9% (32/36) of lesions treated with MW ablation (P=0.6). Complete response was achieved in all lesions ≤2.0cm in diameter in both groups. There was no significant difference in rates of residual foci of HCC lesions between RF and MW ablation groups (P=0.15, Log-rank test). Recurrence rate for 3, 6, 9, and 12months in patients with HCC who underwent RF ablation compared with MW ablation were 6.3%, 3.1%, 3.1% versus 0%, 5.6%, 2.8%, and 2.8%. Progression-Free Survival rates for treated patients with RF ablation of 1, 2, and 3years were 96.9%, 93.8%, and 90.6% and treated with MW ablation therapy were 97.2%, 94.5%, and 91.7, respectively (P=0.98). Conclusion: In conclusion, RF and MW ablation therapy showed no significant difference in the treatment of HCC regarding the complete response, rates of residual foci of untreated disease, and recurrence rate. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Microwave |2 nationallicence | |
| 690 | 7 | |a Radiofrequency |2 nationallicence | |
| 690 | 7 | |a Ablation |2 nationallicence | |
| 690 | 7 | |a Hepatocellular carcinoma |2 nationallicence | |
| 700 | 1 | |a Vogl |D Thomas |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Farshid |D Parviz |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Naguib |D Nagy |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Zangos |D Stefan |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Bodelle |D Boris |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Paul |D Jijo |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Mbalisike |D Emannuel |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Beeres |D Martin |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 700 | 1 | |a Nour-Eldin |D Nour-Eldin |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1829-1837 |x 0942-8925 |q 40:6<1829 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0355-6 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0355-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vogl |D Thomas |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Farshid |D Parviz |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Naguib |D Nagy |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zangos |D Stefan |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bodelle |D Boris |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Paul |D Jijo |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mbalisike |D Emannuel |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Beeres |D Martin |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nour-Eldin |D Nour-Eldin |u Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1829-1837 |x 0942-8925 |q 40:6<1829 |1 2015 |2 40 |o 261 | ||