caa a22 4500 605492336 CHVBK 20210128100514.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-015-0355-6 doi (NATIONALLICENCE)springer-10.1007/s00261-015-0355-6 Ablation therapy of hepatocellular carcinoma: a comparative study between radiofrequency and microwave ablation [Elektronische Daten] [Thomas Vogl, Parviz Farshid, Nagy Naguib, Stefan Zangos, Boris Bodelle, Jijo Paul, Emannuel Mbalisike, Martin Beeres, Nour-Eldin Nour-Eldin] Purpose: The aim of the study is to retrospectively evaluate and compare the therapeutic response of Radiofrequency (RF) and Microwave (MW) ablation therapy of hepatocellular carcinoma (HCC). Materials and Methods: 53 consecutive patients (42 males, 11 females; mean age 59years, range: 40-68, SD: 4.2) underwent CT-guided percutaneous RF and MW ablation of 68 HCC liver lesions. The morphologic tumor response (number, location and size) was evaluated by magnetic resonance imaging. The follow-up protocol was 24h post-ablation then within 3 monthly intervals post-ablation in the first year and 6 monthly intervals thereafter. Results: Complete therapeutic response was noted in 84.4% (27/32) of lesions treated with RFA and in 88.9% (32/36) of lesions treated with MW ablation (P=0.6). Complete response was achieved in all lesions ≤2.0cm in diameter in both groups. There was no significant difference in rates of residual foci of HCC lesions between RF and MW ablation groups (P=0.15, Log-rank test). Recurrence rate for 3, 6, 9, and 12months in patients with HCC who underwent RF ablation compared with MW ablation were 6.3%, 3.1%, 3.1% versus 0%, 5.6%, 2.8%, and 2.8%. Progression-Free Survival rates for treated patients with RF ablation of 1, 2, and 3years were 96.9%, 93.8%, and 90.6% and treated with MW ablation therapy were 97.2%, 94.5%, and 91.7, respectively (P=0.98). Conclusion: In conclusion, RF and MW ablation therapy showed no significant difference in the treatment of HCC regarding the complete response, rates of residual foci of untreated disease, and recurrence rate. Springer Science+Business Media New York, 2015 Microwave nationallicence Radiofrequency nationallicence Ablation nationallicence Hepatocellular carcinoma nationallicence Vogl Thomas Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Farshid Parviz Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Naguib Nagy Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Zangos Stefan Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Bodelle Boris Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Paul Jijo Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Mbalisike Emannuel Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Beeres Martin Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Nour-Eldin Nour-Eldin Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1829-1837 0942-8925 40:6<1829 2015 40 261 https://doi.org/10.1007/s00261-015-0355-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0355-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vogl Thomas Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Farshid Parviz Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Naguib Nagy Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Zangos Stefan Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Bodelle Boris Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Paul Jijo Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Mbalisike Emannuel Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Beeres Martin Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 700 1- Nour-Eldin Nour-Eldin Institute for Diagnostic and Interventional Radiology, Johann Wolfgang Goethe, University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1829-1837 0942-8925 40:6<1829 2015 40 261