Quantitative T2* magnetic resonance imaging for renal iron overload assessment: normal values by age and sex
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| 008 | 210128e20150801xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00261-015-0395-y |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0395-y | ||
| 245 | 0 | 0 | |a Quantitative T2* magnetic resonance imaging for renal iron overload assessment: normal values by age and sex |h [Elektronische Daten] |c [Emanuele Grassedonio, Antonella Meloni, Vincenzo Positano, Daniele De Marchi, Patrizia Toia, Massimo Midiri, Alessia Pepe] |
| 520 | 3 | |a Purpose: Few studies of renal iron content have been performed with multiecho gradient-echo (ME-GRE) T2* magnetic resonance imaging (MRI). We assessed the feasibility and reproducibility of ME-GRE T2* MRI for measuring regional and global renal T2* values, and established the lower limits of normal in healthy subjects, also correlating the measured values with age and sex. Methods: Twenty consecutive healthy subjects (13 men and 7 women, mean age 29.1±7.2years, range 19-42years) underwent MRI examinations using a 1.5 T magnet and an ME-GRE T2* sequence. For each kidney, T2* was measured in anterior, posterolateral, and posteromedial renal parenchymal regions. The mean T2* value was calculated as the average of the two kidneys T2* values. Results: For the mean kidney T2* value, the coefficients of variation for intra- and inter-operator reproducibility were 1.76% and 6.23%, respectively. The lower limit of normal for the mean kidney T2* value was 31ms (median 51.39±10.09). There was no significant difference between left and right kidney T2* values (p=0.578). No significant correlation was found between T2* values and subjects' age or sex. Conclusions: Renal ME-GRE T2* appears to be a feasible and reproducible technique. The renal T2* values showed no dependence on sex or age. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Multiecho T2* |2 nationallicence | |
| 690 | 7 | |a Iron loading |2 nationallicence | |
| 690 | 7 | |a Kidney |2 nationallicence | |
| 690 | 7 | |a Thalassemia |2 nationallicence | |
| 700 | 1 | |a Grassedonio |D Emanuele |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | |
| 700 | 1 | |a Meloni |D Antonella |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Positano |D Vincenzo |u Technologies Department, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy |4 aut | |
| 700 | 1 | |a De Marchi |D Daniele |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Toia |D Patrizia |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | |
| 700 | 1 | |a Midiri |D Massimo |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | |
| 700 | 1 | |a Pepe |D Alessia |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1700-1704 |x 0942-8925 |q 40:6<1700 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0395-y |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0395-y |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Grassedonio |D Emanuele |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Meloni |D Antonella |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Positano |D Vincenzo |u Technologies Department, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a De Marchi |D Daniele |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Toia |D Patrizia |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Midiri |D Massimo |u Istituto di Radiologia, DIBIMED, University of Palermo, Palermo, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Pepe |D Alessia |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1700-1704 |x 0942-8925 |q 40:6<1700 |1 2015 |2 40 |o 261 | ||