caa a22 4500 605492514 CHVBK 20210128100515.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-015-0387-y doi (NATIONALLICENCE)springer-10.1007/s00261-015-0387-y Clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones [Elektronische Daten] [Huanguo Li, Dong He, Qun Lao, Xingcan Chen, Miao Liu, Bingxin Yin, Kaiyu Zhao, Rui Wang, Longxia Chen] Objective: To investigate the clinical value of spectral CT in diagnosis of negative gallstones and common bile duct stones primarily. Methods: All patients diagnosed with negative biliary stones were analyzed and examined by spectral CT scanner retrospectively. Based on acquired raw imaging data, image series were reconstructed as described below: the optimal contrast-to-noise ratio monochromatic energy images, calcium- and fat- based material decomposition images and spectral curve images. All these imaging series were analyzed quantitatively and qualitatively. Results: The contrast between negative stones and adjacent bile was 6.87±5.48 HU on hybrid energy CT images and 47.30±24.05 HU on optimal monochromatic energy CT images. The mean concentration of calcium in bile and negative stones was 19.36±5.12 and 3.88±6.60mg/mL, and the fat in bile and negative stones was 998.48±11.79 and 1035.68±15.36mg/mL. Effective atomic number Z of negative stones (6.60±0.45) was lower than that of bile (7.65±0.13). The slopes of the spectral curves for negative stones were k 90-40KeV=1.43±0.63 and k 140-90KeV=0.19±0.08, and for bile, they were k 90-40KeV=-0.27±0.09 and k 140-90KeV=-0.04±0.01. The same stone showed different densities in different imaging groups. The positive rate of conventional CT images was lower than that of other imaging groups. Conclusion: Spectral CT has a high diagnostic value for negative gallstones or bile duct stones, and material decomposition CT images and spectral curves can make an accurate diagnosis. Springer Science+Business Media New York, 2015 Spectral CT nationallicence Diagnosis nationallicence Negative gallstones nationallicence Bile duct stones nationallicence Li Huanguo The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut He Dong The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut Lao Qun The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut Chen Xingcan The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut Liu Miao The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut Yin Bingxin The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut Zhao Kaiyu The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut Wang Rui The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut Chen Longxia The Department of Neonatology, Children's Hospital of Fudan University, 201102, Shanghai, China aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1587-1594 0942-8925 40:6<1587 2015 40 261 https://doi.org/10.1007/s00261-015-0387-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0387-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Li Huanguo The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut NATIONALLICENCE 700 1- He Dong The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut NATIONALLICENCE 700 1- Lao Qun The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut NATIONALLICENCE 700 1- Chen Xingcan The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut NATIONALLICENCE 700 1- Liu Miao The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut NATIONALLICENCE 700 1- Yin Bingxin The Department of Radiology, 117th Hospital of PLA, No. 14 Lingyin Rd, Xihu district, 310013, Hangzhou, China aut NATIONALLICENCE 700 1- Zhao Kaiyu The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut NATIONALLICENCE 700 1- Wang Rui The Department of Radiology, Hangzhou Children's Hospital, No. 195 Wenhui Rd, Xiacheng district, 310015, Hangzhou, China aut NATIONALLICENCE 700 1- Chen Longxia The Department of Neonatology, Children's Hospital of Fudan University, 201102, Shanghai, China aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1587-1594 0942-8925 40:6<1587 2015 40 261