caa a22 4500 605492549 CHVBK 20210128100516.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-014-0296-5 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0296-5 Use of transabdominal ultrasonography to preoperatively determine T-stage of proven colon cancers [Elektronische Daten] [Susumu Shibasaki, Norihiko Takahashi, Shigenori Homma, Mutsumi Nishida, Tatsushi Shimokuni, Tadashi Yoshida, Hideki Kawamura, Noriko Oyama-Manabe, Kohsuke Kudo, Akinobu Taketomi] Purpose: Although noninvasive and highly informative, transabdominal ultrasonography (US) is not yet an accepted means of staging colorectal cancer preoperatively. This prospective study evaluated the diagnostic accuracy of US in preoperative staging of patients with resectable colon cancers. Methods: A total of 98 patients with primary colon cancer diagnosed by colonoscopy at our institute between January, 2011 and June, 2014 underwent preoperative ultrasonographic tumor staging. Depth of tumor infiltration (T-stage) was assessed by standard means (i.e., extent of mural involvement), analyzing agreement in US and histopathology determinations. Results: All but two colon cancers (at splenic flexure) were detected by US (98%, 96/98). Compared with histopathology, overall accuracy of US in determining T-stage was 64% (61/96), indicating moderate reproducibility (κ coefficient 0.48; 95% CI 0.35-0.62; p<0.001). Using a three-tier approach of graded muscularis propria (MP) involvement (Tis/T1, below MP; T2, within MP; and T3/T4, beyond MP), diagnostic agreement increased to 89% (85/96), with good agreement (κ coefficient 0.77; 95% CI 0.64-0.90; p<0.001). No tumor characteristics or patient demographics influenced diagnostic agreement at any site in the colon. Conclusions: Given the potential to yield valuable information while limiting patient discomfort, US should be reconsidered as a means of assessing colon cancer. Springer Science+Business Media New York, 2014 Colon cancer nationallicence Transabdominal ultrasonography nationallicence Preoperative T-stage diagnosis nationallicence Shibasaki Susumu Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Takahashi Norihiko Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Homma Shigenori Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Nishida Mutsumi Division of Laboratory and Transfusion Medicine, Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut Shimokuni Tatsushi Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Yoshida Tadashi Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Kawamura Hideki Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Oyama-Manabe Noriko Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut Kudo Kohsuke Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut Taketomi Akinobu Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1441-1450 0942-8925 40:6<1441 2015 40 261 https://doi.org/10.1007/s00261-014-0296-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0296-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shibasaki Susumu Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Takahashi Norihiko Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Homma Shigenori Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Nishida Mutsumi Division of Laboratory and Transfusion Medicine, Diagnostic Center for Sonography, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Shimokuni Tatsushi Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Yoshida Tadashi Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Kawamura Hideki Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Oyama-Manabe Noriko Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Kudo Kohsuke Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 700 1- Taketomi Akinobu Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, N15, W7, Kita-Ku, 060-8638, Sapporo, Hokkaido, Japan aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1441-1450 0942-8925 40:6<1441 2015 40 261