Enhancement of radiofrequency ablation of the liver combined with transarterial embolization using various embolic agents
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| 024 | 7 | 0 | |a 10.1007/s00261-014-0332-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-014-0332-5 | ||
| 245 | 0 | 0 | |a Enhancement of radiofrequency ablation of the liver combined with transarterial embolization using various embolic agents |h [Elektronische Daten] |c [Kuniyasu Irie, Manabu Morimoto, Kazushi Numata, Masaaki Kondo, Satoshi Moriya, Yu Shimoyama, Akito Nozaki, Yoshihiro Goda, Satoshi Kobayashi, Makoto Ueno, Shinichi Ohkawa, Katsuaki Tanaka, Shin Maeda] |
| 520 | 3 | |a Purpose: Reducing blood flow in the liver during radiofrequency ablation causes enlargement of the ablation area. In this animal study, we evaluated the extended effects of radiofrequency ablation combined with transarterial embolization using various embolic agents. Methods: We treated 38 radiofrequency ablation lesions after embolization in 13 pigs using the following embolic agents: gelatin sponge (Group A); iodized oil followed by gelatin sponge (Group B); 700-900µm calibrated microspheres (Group C); and 100-300µm calibrated microspheres (Group D). Lesion size and pathological evaluations of these ablation lesions were compared with those receiving radiofrequency ablation alone (control). Results: Both the long- and short-axis diameters of the ablation lesions for Groups A, B, C, and D were significantly longer than those of controls (long axis/short axis for Groups A, B, C, D, and controls were 27.2/23.2, 30.2/26.0, 28.2/22.2, 32.0/24.4, and 23.2mm/18.5mm, respectively) (P<0.05). The long-axis of the ablation lesion for Group D was significantly longer than those for both Groups A and C (P<0.05). At pathological examination, the central ablation lesions showed coagulative necrosis with a surrounding hemorrhagic rim, and the microspheres were fitted to occlude the small arteries in peripheral liver parenchyma in Groups C and D. Conclusions: The extended effects of embolization with small microspheres may be stronger than those with large microspheres and were equal to those with iodized oil followed by gelatin sponge. | |
| 540 | |a Springer Science+Business Media New York, 2014 | ||
| 690 | 7 | |a Radiofrequency |2 nationallicence | |
| 690 | 7 | |a Embolization |2 nationallicence | |
| 690 | 7 | |a Microspheres |2 nationallicence | |
| 690 | 7 | |a Hepatocellular carcinoma |2 nationallicence | |
| 690 | 7 | |a Coagulation |2 nationallicence | |
| 690 | 7 | |a Combination |2 nationallicence | |
| 700 | 1 | |a Irie |D Kuniyasu |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Morimoto |D Manabu |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Numata |D Kazushi |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Kondo |D Masaaki |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Moriya |D Satoshi |u Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Shimoyama |D Yu |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Nozaki |D Akito |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Goda |D Yoshihiro |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Kobayashi |D Satoshi |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Ueno |D Makoto |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Ohkawa |D Shinichi |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Tanaka |D Katsuaki |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | |
| 700 | 1 | |a Maeda |D Shin |u Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1821-1828 |x 0942-8925 |q 40:6<1821 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-014-0332-5 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-014-0332-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Irie |D Kuniyasu |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Morimoto |D Manabu |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Numata |D Kazushi |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kondo |D Masaaki |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Moriya |D Satoshi |u Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shimoyama |D Yu |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nozaki |D Akito |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Goda |D Yoshihiro |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kobayashi |D Satoshi |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ueno |D Makoto |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ohkawa |D Shinichi |u Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center, 2-3-2 Nakao, Asahi-ku, 241-8515, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tanaka |D Katsuaki |u Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Maeda |D Shin |u Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1821-1828 |x 0942-8925 |q 40:6<1821 |1 2015 |2 40 |o 261 | ||