caa a22 4500 605492638 CHVBK 20210128100516.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-014-0320-9 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0320-9 Clinical outcome comparison between TIPS and EBL in patients with cirrhosis and portal vein thrombosis [Elektronische Daten] [Zhu Wang, He Zhao, Xiaoze Wang, Hailong Zhang, Mingshan Jiang, Jiaywei Tsauo, Xuefeng Luo, Li Yang, Xiao Li] The aim of this study is to compare the clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) and endoscopic band ligation (EBL) in patients with cirrhosis and portal vein thrombosis (PVT). We retrospectively reviewed the January to September 2010 data from our database and included 25 patients with cirrhosis and PVT who underwent successful TIPS creation. We selected another 25 patients who underwent EBL matching for age, sex, and Child-Pugh-Turcotte class. The outcome measures included changes in the PVT status before and after the treatments, the rebleeding rate, and the overall survival. The mean follow-up was 25.1±8.7months in the EBL group and 25.6±8.5months in the TIPS group (P=0.85). After treatments, the PVT severity improved in 40% and worsened in 25% of patients who did not undergo TIPS, compared with 87% and none of the patients who underwent TIPS (P<0.001). Previous splenectomy (OR 0.13, 95% CI 0.02-0.76, P=0.024) and patency status of TIPS (OR 20.8, 95% CI 3.0-141.8, P=0.002) were the independent factors associated with PVT disappearance. The 1- and 2-year rebleeding rates were, respectively, 44.6% and 59.0% in the EBL group, and 12.5% and 25.2% in the TIPS group (P=0.002). The 1- and 2-year survival rates were, respectively, 95.7% and 85.2% in the EBL group, and 96% and 78.7% in the TIPS group (P=0.203). The MELD score was the only independent predictive factor for survival (HR 1.73, 95% CI 1.27-2.37, P=0.001). Compared with EBL, TIPS contributed to PVT improvement and reduced the risk of rebleeding without providing a survival benefit for patients with PVT. Springer Science+Business Media New York, 2014 Portal hypertension nationallicence Variceal bleeding nationallicence Portal vein thrombosis nationallicence Wang Zhu Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Zhao He Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Wang Xiaoze Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Zhang Hailong Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Jiang Mingshan Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Tsauo Jiaywei Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Luo Xuefeng Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Yang Li Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Li Xiao Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1813-1820 0942-8925 40:6<1813 2015 40 261 https://doi.org/10.1007/s00261-014-0320-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0320-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Zhu Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Zhao He Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Wang Xiaoze Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Zhang Hailong Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Jiang Mingshan Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Tsauo Jiaywei Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Luo Xuefeng Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Yang Li Department of Gastroenterology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 700 1- Li Xiao Institution of Intervention Radiology, West China Hospital, Sichuan University, 37# Guoxue Lane, 610041, Chengdu, Sichuan, China aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1813-1820 0942-8925 40:6<1813 2015 40 261