Prediction of esophageal varices in cirrhotic patients with apparent diffusion coefficient of the spleen
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| 024 | 7 | 0 | |a 10.1007/s00261-015-0391-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0391-2 | ||
| 245 | 0 | 0 | |a Prediction of esophageal varices in cirrhotic patients with apparent diffusion coefficient of the spleen |h [Elektronische Daten] |c [Ahmed Razek, Samia Massoud, Mona Azziz, Mahmoud El-Bendary, Khaled Zalata, Enas Motawea] |
| 520 | 3 | |a Purpose: To predict esophageal varices in cirrhotic patients with apparent diffusion coefficient (ADC) of the spleen and to correlate the ADC with clinical and laboratory biomarkers of esophageal varices. Materials and methods: This study was conducted upon 40 patients (28 male, 12 female; age ranged 19-45years; mean age=33years) with biopsy-proven cirrhotic liver. Twenty age- and sex-matched healthy volunteers were included as a control group. Patients with varices (n=15) and without varices (n=25) and volunteers underwent echo-planar diffusion-weighted MR imaging of the abdomen with b factors of 0, 400, and 800s/mm2. The ADC maps of the abdomen were reconstructed. The ADC values of the spleen were calculated and correlated with the Child score, platelet count, and prothrombin time. Results: The mean ADC value of the spleen in cirrhotic patients (1.34±0.05×10−3mm2/s) was significantly different (P=0.001) from that of volunteers (0.87±0.04×10−3mm2/s). The ADC of the spleen in cirrhotic patients with varices (1.49±0.05×10−3mm2/s) was significantly different (P=0.001) from that of patients without varices (1.11±0.06×10−3mm2/s). The cut-off ADC value of the spleen used for prediction of cirrhosis and varices was 1.15 and 1.29×10−3mm2/s with areas under the curve were 0.872 and 0.889, respectively. The ADC value of the spleen was correlated with the splenic volume (r=0.862; P=0.001), Child score (r=0.742; P=0.001), platelet count (r=-0.698; P=0.01), and prothrombin time (r=0.684; P=0.01). Conclusion: The ADC value of the spleen can predict esophageal varices in cirrhotic patients and is well correlated with the clinical and laboratory biomarkers of esophageal varices. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Diffusion |2 nationallicence | |
| 690 | 7 | |a MR imaging |2 nationallicence | |
| 690 | 7 | |a Cirrhosis |2 nationallicence | |
| 690 | 7 | |a Varices |2 nationallicence | |
| 700 | 1 | |a Razek |D Ahmed |u Department of Diagnostic Radiology, Mansoura Faculty of Medicine, 13351, Mansoura, Egypt |4 aut | |
| 700 | 1 | |a Massoud |D Samia |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | |
| 700 | 1 | |a Azziz |D Mona |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | |
| 700 | 1 | |a El-Bendary |D Mahmoud |u Department of Tropical Medicine, Mansoura Faculty of Medicine, Mansoura, Egypt |4 aut | |
| 700 | 1 | |a Zalata |D Khaled |u Department of Pathology, Mansoura Faculty of Medicine, Mansoura, Egypt |4 aut | |
| 700 | 1 | |a Motawea |D Enas |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1465-1469 |x 0942-8925 |q 40:6<1465 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0391-2 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0391-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Razek |D Ahmed |u Department of Diagnostic Radiology, Mansoura Faculty of Medicine, 13351, Mansoura, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Massoud |D Samia |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Azziz |D Mona |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a El-Bendary |D Mahmoud |u Department of Tropical Medicine, Mansoura Faculty of Medicine, Mansoura, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zalata |D Khaled |u Department of Pathology, Mansoura Faculty of Medicine, Mansoura, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Motawea |D Enas |u Department of Tropical Medicine, Al-Azhar Faculty of Medicine for Girls, Cairo, Egypt |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/6(2015-08-01), 1465-1469 |x 0942-8925 |q 40:6<1465 |1 2015 |2 40 |o 261 | ||