MDCT findings of pancreatic metastases according to primary tumors

Verfasser / Beitragende:
[Tae Choi, Se Kim, Cheong-Il Shin, Joon Han, Byung Choi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/6(2015-08-01), 1595-1607
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0299-2  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0299-2 
245 0 0 |a MDCT findings of pancreatic metastases according to primary tumors  |h [Elektronische Daten]  |c [Tae Choi, Se Kim, Cheong-Il Shin, Joon Han, Byung Choi] 
520 3 |a Purpose: To describe the clinical and MDCT findings of metastatic pancreatic tumors (MPTs) from various primary malignancies and to determine whether there are characteristic imaging features of MPTs according to the various histologies of primary tumors. Materials and methods: Thirty-six patients with pathologically proven MPTs who underwent MDCT were retrospectively enrolled. Mean survival and factors associated with prolonged survival were analyzed using multivariate Cox regression analysis. MDCT was analyzed for the location, number, margin, and pattern and degree of enhancements of MPTs and main pancreatic duct (MPD) dilatations. Significant differences in CT features among the various histologies of MPTs were determined using the χ 2 or Fisher's exact test. Results: The most common primary tumors metastasized to the pancreas were renal cell carcinomas (RCC) (n=17), gastric cancers (n=7), and colorectal cancers (n=5). Mean survival was significantly different between RCC (106.7months) and non-RCC (25.1months) metastases (P<0.001). A primary tumor of RCC was the only factor associated with prolonged survival (hazard ratio: 0.106, P=0.003). On MDCT, pancreatic metastases from RCC were frequently multifocal, located at the center of the pancreas, usually homogeneous and well-defined with early wash-in and persistent enhancement; non-RCC metastases tended to be solitary, located off-center (P<0.05), and appeared as heterogeneous, ill-defined nodules with persistent low attenuation (P<0.05). Conclusion: Various non-RCC tumors as well as RCCs metastasize to the pancreas but a primary tumor of RCC is the only factor associated with prolonged survival. MDCT features of MPTs are significantly different between the RCC and non-RCC metastases, potentially aiding in their differentiation and selection of the most appropriate management options for these patients. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Metastasis  |2 nationallicence 
690 7 |a Pancreas  |2 nationallicence 
690 7 |a Multidetector computed tomography  |2 nationallicence 
700 1 |a Choi  |D Tae  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Kim  |D Se  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Shin  |D Cheong-Il  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Han  |D Joon  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
700 1 |a Choi  |D Byung  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1595-1607  |x 0942-8925  |q 40:6<1595  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0299-2  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0299-2  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Tae  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Se  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shin  |D Cheong-Il  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Han  |D Joon  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Byung  |u Department of Radiology, Institute of Radiation Medicine, Seoul National University Hospital, 101 Daehangno, Jongno-gu, 110-744, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1595-1607  |x 0942-8925  |q 40:6<1595  |1 2015  |2 40  |o 261