A case of β-catenin-positive hepatocellular adenoma with MR imaging sign of diffuse intratumoral fat deposition

Verfasser / Beitragende:
[Masaya Ishii, Junichi Kazaoka, Junichi Fukushima, Mariko Gunji, Toru Aoyama, Toshio Fukusato, Keiji Sano, Fukuo Kondo, Toru Takeshita, Shigeru Furui, Masaaki Akahane]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/6(2015-08-01), 1487-1491
Format:
Artikel (online)
ID: 605492875
LEADER caa a22 4500
001 605492875
003 CHVBK
005 20210128100517.0
007 cr unu---uuuuu
008 210128e20150801xx s 000 0 eng
024 7 0 |a 10.1007/s00261-014-0342-3  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0342-3 
245 0 2 |a A case of β-catenin-positive hepatocellular adenoma with MR imaging sign of diffuse intratumoral fat deposition  |h [Elektronische Daten]  |c [Masaya Ishii, Junichi Kazaoka, Junichi Fukushima, Mariko Gunji, Toru Aoyama, Toshio Fukusato, Keiji Sano, Fukuo Kondo, Toru Takeshita, Shigeru Furui, Masaaki Akahane] 
520 3 |a Hepatocellular adenoma (HCA) is a rare primary benign tumor of the liver, which occurs predominantly in young and middle-aged women. Recently, the subclassification of HCA was proposed by the Bordeaux group. Subsequently, characteristic radiological and clinical features have been revealed in each HCA subtype. According to the previous literature, diffuse intratumoral fat deposition is a very common finding in hepatocyte nuclear factor 1α-negative HCA, but this finding has been reported in β-catenin-positive HCA in the literature for only one case. In this case report, we report the second case of β-catenin-positive HCA with MR imaging sign of diffuse intratumoral fat deposition, confirmed immunohistologically on the basis of a surgical specimen. In addition, our case showed hypovascularity and isointensity on the hepatobiliary phase which have been reported as characteristic findings in β-catenin-positive HCA. Diffuse intratumoral fat deposition can be observed in β-catenin-positive HCA, which has a greater probability of malignant transformation than other types of HCA. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a β-Catenin-positive hepatocellular adenoma  |2 nationallicence 
690 7 |a Hepatocellular adenoma  |2 nationallicence 
690 7 |a Diffuse intratumoral fat deposition  |2 nationallicence 
690 7 |a Diffuse intratumoral steatosis  |2 nationallicence 
700 1 |a Ishii  |D Masaya  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
700 1 |a Kazaoka  |D Junichi  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
700 1 |a Fukushima  |D Junichi  |u Department of Pathology, Gyoda General Hospital, 376 Mochida, 361-0056, Gyoda-shi, Saitama, Japan  |4 aut 
700 1 |a Gunji  |D Mariko  |u Department of Diagnostic Pathology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
700 1 |a Aoyama  |D Toru  |u Division of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, 350-8550, Kawagoe-shi, Saitama, Japan  |4 aut 
700 1 |a Fukusato  |D Toshio  |u Department of Pathology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
700 1 |a Sano  |D Keiji  |u Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
700 1 |a Kondo  |D Fukuo  |u Department of Pathology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
700 1 |a Takeshita  |D Toru  |u Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
700 1 |a Furui  |D Shigeru  |u Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
700 1 |a Akahane  |D Masaaki  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1487-1491  |x 0942-8925  |q 40:6<1487  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0342-3  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0342-3  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ishii  |D Masaya  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kazaoka  |D Junichi  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fukushima  |D Junichi  |u Department of Pathology, Gyoda General Hospital, 376 Mochida, 361-0056, Gyoda-shi, Saitama, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Gunji  |D Mariko  |u Department of Diagnostic Pathology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aoyama  |D Toru  |u Division of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, 350-8550, Kawagoe-shi, Saitama, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fukusato  |D Toshio  |u Department of Pathology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sano  |D Keiji  |u Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kondo  |D Fukuo  |u Department of Pathology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Takeshita  |D Toru  |u Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Furui  |D Shigeru  |u Department of Radiology, Teikyo University School of Medicine, 2-11-1 Kaga, 173-8606, Itabashi-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Akahane  |D Masaaki  |u Department of Radiology, NTT Medical Center Tokyo, 5-9-22 Higashigotanda, 141-0022, Shinagawa-ku, Tokyo, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/6(2015-08-01), 1487-1491  |x 0942-8925  |q 40:6<1487  |1 2015  |2 40  |o 261