caa a22 4500 605492948 CHVBK 20210128100518.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00261-015-0460-6 doi (NATIONALLICENCE)springer-10.1007/s00261-015-0460-6 MR-PET co-registration in upper abdominal imaging: quantitative comparison of two different T1-weighted gradient echo sequences: initial observations [Elektronische Daten] [Miguel Ramalho, Mamdoh AlObaidy, Lauren Burke, Brian Dale, Kiran Busireddy, Terence Wong, Abdulaziz AlSugair, Richard Semelka] Purpose: The purpose of this study is to quantitatively compare the accuracy of spatial registration of Cartesian breath-hold 3D-GRE and non-respiratory-triggered free-breathing radial 3D-GRE images with PET data acquisition on whole-body hybrid MR-PET system. Materials and methods: Eight patients (six men and two women; mean age, 56.6±5.5 years) with nine ablated hepatocellular carcinomas constituted our study population. Spatial coordinates (x, y, z) of the estimated isocenters of the ablated areas were independently determined by two radiologists. Both T1-weighted sequences were performed in the axial plane. Distance between the isocenter of the lesion on PET images and on both T1-weighted images was measured, and misregistration was calculated. Statistical analysis was performed using Student t test. Results: Misalignment values of the hepatic ablation zones between PET and MR images were calculated at 4.94±1.35 mm (reader 1) and 4.89±2.21 mm (reader 2) for Cartesian 3D-GRE sequence, and 2.48±0.65 mm (reader 1) and 2.72±0.44 mm (reader 2) for the radial 3D-GRE sequence, with p values of 0.0011 and 0.0133, respectively. Conclusion: Radial 3D-GRE offers improved registration accuracy with PET, supporting the use of this T1-weighted sequence in upper abdominal MR-PET studies. Springer Science+Business Media New York, 2015 MR-PET nationallicence Registration nationallicence Alignment nationallicence Radial nationallicence Cartesian nationallicence 3D-GRE nationallicence Ramalho Miguel Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut AlObaidy Mamdoh Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut Burke Lauren Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut Dale Brian Siemens Medical Solution, Cary, NC, USA aut Busireddy Kiran Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut Wong Terence Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut AlSugair Abdulaziz Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia aut Semelka Richard Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1426-1431 0942-8925 40:6<1426 2015 40 261 https://doi.org/10.1007/s00261-015-0460-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0460-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ramalho Miguel Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- AlObaidy Mamdoh Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Burke Lauren Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Dale Brian Siemens Medical Solution, Cary, NC, USA aut NATIONALLICENCE 700 1- Busireddy Kiran Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Wong Terence Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- AlSugair Abdulaziz Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia aut NATIONALLICENCE 700 1- Semelka Richard Department of Radiology, University Of North Carolina at Chapel Hill, Old Clinic Bldg., CB 7510 - 2001, 27599-7510, Chapel Hill, NC, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/6(2015-08-01), 1426-1431 0942-8925 40:6<1426 2015 40 261