Xanthogranulomatous cholecystitis: diagnostic performance of US, CT, and MRI for differentiation from gallbladder carcinoma

Verfasser / Beitragende:
[Eun Lee, Jung Kim, Ijin Joo, Jae Lee, Joon Han, Byung Choi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/7(2015-10-01), 2281-2292
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-015-0432-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-015-0432-x 
245 0 0 |a Xanthogranulomatous cholecystitis: diagnostic performance of US, CT, and MRI for differentiation from gallbladder carcinoma  |h [Elektronische Daten]  |c [Eun Lee, Jung Kim, Ijin Joo, Jae Lee, Joon Han, Byung Choi] 
520 3 |a Objectives: The purpose of this study is to evaluate the diagnostic performance of HRUS, CT, and MRI for differentiating xanthogranulomatous cholecystitis (XGC) from gallbladder (GB) cancer. Materials and Methods: Patients with surgically proven XGC (n=40) and GB cancer (n=44), who had undergone at least one HRUS (n=43), CT (n=82), or MRI (n=34) examination between 2000 and 2012, were included. Two radiologists retrospectively graded the likelihood of XGC or GB cancer using a 5-point confidence scale; they also assessed the imaging features. Statistical analyses were performed using ROC, ANOVA, and Fisher's exact test. Results: Diagnostic performance of MRI was better than HRUS for differentiating XGC from GB cancer (AUCs=0.867 and 0.911 vs. AUCs=0.818 and 0.86). However, HRUS showed a better performance than CT (AUCs=0.818 and 0.86 vs. AUCs=0.806 and 0.84) with moderate to excellent agreement (κ=0.48-0.83). Statistically common findings for XGC included non-focal thickening, smooth GB wall, presence of intramural nodules, type I enhancement of wall, transient hepatic attenuation difference, and continuity of mucosa (p<0.05). Co-existence of gallstones (OR=16.5), non-focal thickening (OR=14.7), and collapsed lumen (OR=13.0) on HRUS, and type I enhancement on CT (OR=3.52) were independently associated with XGC (p<0.05). Conclusion: Although MRI showed a better performance than both HRUS and CT, HRUS showed a better performance than CT. The co-existence of gallstones, non-focal thickening, and collapsed lumen on HRUS was independently associated with XGC. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Cholecystitis  |2 nationallicence 
690 7 |a Gallbladder neoplasm  |2 nationallicence 
690 7 |a Ultrasonography  |2 nationallicence 
690 7 |a Multidetector computed tomography  |2 nationallicence 
690 7 |a Magnetic resonance imaging  |2 nationallicence 
700 1 |a Lee  |D Eun  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
700 1 |a Kim  |D Jung  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
700 1 |a Joo  |D Ijin  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
700 1 |a Lee  |D Jae  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
700 1 |a Han  |D Joon  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
700 1 |a Choi  |D Byung  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/7(2015-10-01), 2281-2292  |x 0942-8925  |q 40:7<2281  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-015-0432-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-015-0432-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Eun  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Jung  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Joo  |D Ijin  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Jae  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Han  |D Joon  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Byung  |u Department of Radiology, Seoul National University Hospital, Seoul, South Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/7(2015-10-01), 2281-2292  |x 0942-8925  |q 40:7<2281  |1 2015  |2 40  |o 261