caa a22 4500 60549309X CHVBK 20210128100519.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0432-x doi (NATIONALLICENCE)springer-10.1007/s00261-015-0432-x Xanthogranulomatous cholecystitis: diagnostic performance of US, CT, and MRI for differentiation from gallbladder carcinoma [Elektronische Daten] [Eun Lee, Jung Kim, Ijin Joo, Jae Lee, Joon Han, Byung Choi] Objectives: The purpose of this study is to evaluate the diagnostic performance of HRUS, CT, and MRI for differentiating xanthogranulomatous cholecystitis (XGC) from gallbladder (GB) cancer. Materials and Methods: Patients with surgically proven XGC (n=40) and GB cancer (n=44), who had undergone at least one HRUS (n=43), CT (n=82), or MRI (n=34) examination between 2000 and 2012, were included. Two radiologists retrospectively graded the likelihood of XGC or GB cancer using a 5-point confidence scale; they also assessed the imaging features. Statistical analyses were performed using ROC, ANOVA, and Fisher's exact test. Results: Diagnostic performance of MRI was better than HRUS for differentiating XGC from GB cancer (AUCs=0.867 and 0.911 vs. AUCs=0.818 and 0.86). However, HRUS showed a better performance than CT (AUCs=0.818 and 0.86 vs. AUCs=0.806 and 0.84) with moderate to excellent agreement (κ=0.48-0.83). Statistically common findings for XGC included non-focal thickening, smooth GB wall, presence of intramural nodules, type I enhancement of wall, transient hepatic attenuation difference, and continuity of mucosa (p<0.05). Co-existence of gallstones (OR=16.5), non-focal thickening (OR=14.7), and collapsed lumen (OR=13.0) on HRUS, and type I enhancement on CT (OR=3.52) were independently associated with XGC (p<0.05). Conclusion: Although MRI showed a better performance than both HRUS and CT, HRUS showed a better performance than CT. The co-existence of gallstones, non-focal thickening, and collapsed lumen on HRUS was independently associated with XGC. Springer Science+Business Media New York, 2015 Cholecystitis nationallicence Gallbladder neoplasm nationallicence Ultrasonography nationallicence Multidetector computed tomography nationallicence Magnetic resonance imaging nationallicence Lee Eun Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Kim Jung Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Joo Ijin Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Lee Jae Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Han Joon Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Choi Byung Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2281-2292 0942-8925 40:7<2281 2015 40 261 https://doi.org/10.1007/s00261-015-0432-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0432-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Eun Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 700 1- Kim Jung Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 700 1- Joo Ijin Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 700 1- Lee Jae Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 700 1- Han Joon Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 700 1- Choi Byung Department of Radiology, Seoul National University Hospital, Seoul, South Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2281-2292 0942-8925 40:7<2281 2015 40 261