The target sign in colorectal liver metastases: an atypical Gd-EOB-DTPA "uptake” on the hepatobiliary phase of MR imaging
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| 008 | 210128e20151001xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00261-015-0488-7 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0488-7 | ||
| 245 | 0 | 4 | |a The target sign in colorectal liver metastases: an atypical Gd-EOB-DTPA "uptake” on the hepatobiliary phase of MR imaging |h [Elektronische Daten] |c [Vincenza Granata, Orlando Catalano, Roberta Fusco, Fabiana Tatangelo, Daniela Rega, Guglielmo Nasti, Antonio Avallone, Mauro Piccirillo, Francesco Izzo, Antonella Petrillo] |
| 520 | 3 | |a Purpose: To describe the MRI findings in colorectal cancer liver metastases using gadoxetic acid (Gd-EOB-DTPA), with special emphasis on the target feature seen on the hepatobiliary phase. Material and methods: The medical records of 45 colorectal cancer patients with an overall number of 150 liver metastases were reviewed. All patients underwent Gd-EOB-DTPA-enhanced MRI before any kind of treatment. We retrospectively evaluated, for each lesion, the signal intensity on the T1-weighted, T2-weighted, and diffusion-weighted images. Additionally, the enhancement pattern during the arterial-, portal-, equilibrium-, and hepatobiliary-phase was assessed. Fourteen lesions had a pathological correlation. Results: Lesions size was 5-40 mm (mean 15 mm). All metastases were hypointense on T1-w imaging. Ninety-nine lesions (66%) had a central area of very high signal intensity on T2-w imaging. Fifty-one metastases (34%) were hyperintense on the T2-w images. In DWI, all lesions had a restricted diffusion. The mean ADC value was 1.31×10−3mm2/s (range 1.10-1.45×10−3mm2/s). During the arterial-phase imaging, 61 lesions (41%) showed a rim enhancement, while 89 lesions (59%) appeared as hypointense. All lesions had low signal intensity in the portal and equilibrium phase. Thirty-nine percent of the lesions also showed an enhancing rim on the portal-phase images. During the hepatobiliary phase, 80 lesions (53.3%) were hypointense, while 70 lesions (46.7%) had a target appearance. Conclusion: A number of metastases show an atypical contrast medium uptake during the hepatobiliary phase of gadoxetic acid-enhanced MRI, consisting in a target appearance. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Colorectal cancer |2 nationallicence | |
| 690 | 7 | |a Liver metastasis |2 nationallicence | |
| 690 | 7 | |a Magnetic resonance imaging |2 nationallicence | |
| 690 | 7 | |a Gadoxetic acid |2 nationallicence | |
| 700 | 1 | |a Granata |D Vincenza |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Catalano |D Orlando |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Fusco |D Roberta |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Tatangelo |D Fabiana |u Department of Pathology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Rega |D Daniela |u Department of Colorectal Surgical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Nasti |D Guglielmo |u Department of Colorectal Medical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Avallone |D Antonio |u Department of Abdominal Medical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Piccirillo |D Mauro |u Department of Hepatobiliary Surgery, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Izzo |D Francesco |u Department of Hepatobiliary Surgery, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 700 | 1 | |a Petrillo |D Antonella |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/7(2015-10-01), 2364-2371 |x 0942-8925 |q 40:7<2364 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0488-7 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0488-7 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Granata |D Vincenza |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Catalano |D Orlando |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fusco |D Roberta |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tatangelo |D Fabiana |u Department of Pathology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Rega |D Daniela |u Department of Colorectal Surgical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nasti |D Guglielmo |u Department of Colorectal Medical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Avallone |D Antonio |u Department of Abdominal Medical Oncology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Piccirillo |D Mauro |u Department of Hepatobiliary Surgery, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Izzo |D Francesco |u Department of Hepatobiliary Surgery, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Petrillo |D Antonella |u First Department of Radiology, Istituto Nazionale Tumori Fondazione G.Pascale, via Mariano Semmola, 80131, Naples, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/7(2015-10-01), 2364-2371 |x 0942-8925 |q 40:7<2364 |1 2015 |2 40 |o 261 | ||