caa a22 4500 605493189 CHVBK 20210128100519.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0370-7 doi (NATIONALLICENCE)springer-10.1007/s00261-015-0370-7 Multidetector CT detection of peritoneal metastases: evaluation of sensitivity between standard 2.5mm axial imaging and maximum-intensity-projection (MIP) reconstructions [Elektronische Daten] [Corey Jensen, Rafael Vicens-Rodriguez, Nicolaus Wagner-Bartak, Patricia Fox, Silvana Faria, Ivan Carrion, Aliya Qayyum, Eric Tamm] Objective: Our purpose was to evaluate the sensitivity of multidetector CT for the detection of peritoneal metastases between standard 2.5mm axial imaging and maximum-intensity-projection (MIP) reconstructions. Materials and methods: The Institutional Review Board approved this retrospective study and waived the need to obtain patient consent. We retrospectively identified 36 patients with pancreatic adenocarcinoma and peritoneal metastatic disease who underwent a pancreatic protocol CT examination of the abdomen and pelvis between January 2012 and January 2014. Three independent radiologists reviewed a randomized combination of standard axial (2.5mm reconstructed thickness, 2.5mm interval) and axial MIP reconstructions (6, 3mm interval) over two sessions. Each reader recorded metastasis location in PACS. Subsequent consensus review by two radiologists determined the final number and size of metastases. Results: The reviewers found 328 peritoneal implants in 36 patients. After accounting for the size, location, and number of lesions as well as multiple readers, a generalized estimating equations model showed that the statistical combination of MIP with standard technique significantly increased the odds of correctly identifying a lesion (OR 2.16; 95% CI 1.86-2.51; p value<0.0001) compared to standard technique alone. MIP reconstruction as a standalone technique was less sensitive compared to standard technique alone (OR 0.81; 95% CI 0.65-0.99; p value=0.0468). When compared to standard axial imaging, evaluation via MIP reconstructions resulted in the identification of an additional 50 (15%), 45 (14%), and 55 (17%) lesions by Readers 1-3, respectively. Conclusion: The axial 6mm MIP series is complimentary in the CT evaluation of peritoneal metastases. MIP reconstruction evaluation identified a significant number of additional lesions, but is not adequate as a standalone technique for peritoneal cavity assessment. Springer Science+Business Media New York, 2015 MIP nationallicence Maximum intensity projection nationallicence Peritoneal metastases nationallicence Peritoneal evaluation nationallicence CT nationallicence Jensen Corey Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Vicens-Rodriguez Rafael Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Wagner-Bartak Nicolaus Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Fox Patricia Department of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA aut Faria Silvana Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Carrion Ivan University Hospital Joan XXIII (Tarragona), Avda. Jaume Balmes, XX, X-X, 08800, Vilanova i la Geltru Barcelona, Spain aut Qayyum Aliya Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Tamm Eric Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2167-2172 0942-8925 40:7<2167 2015 40 261 https://doi.org/10.1007/s00261-015-0370-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0370-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jensen Corey Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 700 1- Vicens-Rodriguez Rafael Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 700 1- Wagner-Bartak Nicolaus Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 700 1- Fox Patricia Department of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA aut NATIONALLICENCE 700 1- Faria Silvana Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 700 1- Carrion Ivan University Hospital Joan XXIII (Tarragona), Avda. Jaume Balmes, XX, X-X, 08800, Vilanova i la Geltru Barcelona, Spain aut NATIONALLICENCE 700 1- Qayyum Aliya Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 700 1- Tamm Eric Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, 77030-4009, Houston, TX, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2167-2172 0942-8925 40:7<2167 2015 40 261