caa a22 4500 605493367 CHVBK 20210128100520.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0408-x doi (NATIONALLICENCE)springer-10.1007/s00261-015-0408-x Value of magnetic resonance imaging in evaluating the pancreatic allograft transplant complications [Elektronische Daten] [Yubao Liu, Fatih Akisik, Temel Tirkes, Mark Tann, Kumaresan Sandrasegaran, S. Gregory Jennings, Chen Lin, Bharat Kakarala, Jonathan Fridell, John Powelson, Changhong Liang] Purpose: To retrospectively investigate the value of magnetic resonance imaging (MRI) in detecting complications following pancreas transplant. Materials and methods: Institutional review board approved this retrospective HIPAA-compliant study and waived informed patient consent. We identified all allograft pancreas transplant patients at our institution from 2001 to January 2014 who had all pertinent post-transplant imaging and clinical data available. Transplant type was documented. Patients were divided into two groups according to post-transplant period (group A; <12months, group B; ≥12months). We evaluated the parenchymal enhancement using contrast-enhanced MRI of the allograft and determined the mean percentage of parenchymal enhancement (MPPE) overall and in various abnormalities, the vessel patency, any peripancreatic fluid collection, and the ductal anatomy. We correlated these with clinical results using t test, χ 2, and Fisher's exact test; p<0.05 was considered significant. Results: 51 patients (34 male, mean age 43.7years) were identified, 28 (55%) of whom had abnormal imaging findings; transplant rejection-related necrosis (n=7), fluid collections (n=7), vascular stenosis (n=4), isolated venous thromboses (n=3), acute pancreatitis (n=3), pancreatic and peripancreatic abscesses (n=2), pseudoaneurysm (n=1), and small-bowel obstruction (n=1). Pre vs. post-contrast pancreatic MPPE at 1min was 120% in the normal allografts and 115% in the allografts with pancreatitis and without necrosis (p>0.05). MPPE at 1min was only 9% in the allografts rejections with necrosis/infarction. More complications were found in group A than group B (p<0.05). Conclusions: Contrast-enhanced MRI is useful for the non-invasive assessment of pancreas transplant complications. Springer Science+Business Media New York, 2015 Pancreas transplant nationallicence Complication nationallicence Magnetic resonance imaging nationallicence Liu Yubao Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, 510080, Guangzhou, China aut Akisik Fatih Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Tirkes Temel Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Tann Mark Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Sandrasegaran Kumaresan Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Gregory Jennings S. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Lin Chen Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Kakarala Bharat Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Fridell Jonathan Department of Surgery, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Powelson John Department of Surgery, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut Liang Changhong Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, 510080, Guangzhou, China aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2384-2390 0942-8925 40:7<2384 2015 40 261 https://doi.org/10.1007/s00261-015-0408-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0408-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Liu Yubao Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, 510080, Guangzhou, China aut NATIONALLICENCE 700 1- Akisik Fatih Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Tirkes Temel Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Tann Mark Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Sandrasegaran Kumaresan Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Gregory Jennings S. Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Lin Chen Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Kakarala Bharat Department of Radiology and Imaging Sciences, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Fridell Jonathan Department of Surgery, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Powelson John Department of Surgery, Indiana University School of Medicine, 550 N. University Blvd, 46202, Indianapolis, IN, USA aut NATIONALLICENCE 700 1- Liang Changhong Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 106 Zhongshan Er Road, 510080, Guangzhou, China aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2384-2390 0942-8925 40:7<2384 2015 40 261