caa a22 4500 605493650 CHVBK 20210128100522.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0462-4 doi (NATIONALLICENCE)springer-10.1007/s00261-015-0462-4 The initial experience of the upper abdominal CT angiography using low-concentration contrast medium on dual energy spectral CT [Elektronische Daten] [Lei Xin, Xiaotang Yang, Ning Huang, Xiaosong Du, Jianxin Zhang, Yanyan Wang, Lina Hou, Jinfang Gao] Objective: To investigate the feasibility of using Spectral CT imaging with low contrast medium in abdominal CT angiography (CTA). Subjects and methods: 70 consecutive patients (40 men, 42.6±20.4years; 30 women, 46.7±18.8years) with suspected abdominal focal lesions were referred to CTA exam. They were randomly assigned into two groups. Group A: 35 patients underwent conventional CT scan of Tube voltage 120kVp, automatic current modulation with a Noise Index of 12, ASIR 30%, and injected with Iohexol (350mgI/ml). Group B: 35 patients underwent Spectral CT Imaging, with Tube current of 600mA, injected with Iodixanol (270mgI/ml). The optimal mono-energy keV was achieved using the optimal contrast noise ratio in abdominal aorta at the renal artery level relative to the erector spine muscle. Both groups were injected with an injection rate of 3.5ml/s, and a contrast volume of 1.5ml/kg body weight. The Hounsfield units (HU) and noise of the bilateral renal arteries and muscle of both groups, as well as the optimal monochromatic image set of Group B were measured. Two radiologists assessed all images with a 5-points scale. CTDIvol and DLP were recorded. Data were analyzed using student t test. Results: The total iodine intake of Group B was 28% lower than that of Group A. The CNR of abdomen artery, celiac trunk, superior mesenteric artery, and renal artery in spectral group (at the best mono-energy of 53.0keV) were higher than those in conventional CTA group (p<0.001). The subjective image quality score of spectral CTA group was also rated higher than conventional CTA group (p<0.001). CTDIvol, DLP, and effective dose of spectral group were all lower than conventional group, but there were no significant differences (p>0.05). Conclusion: With 28% contrast medium reduction and reduced radiation dose, CT angiography using spectral imaging and lower concentration contrast agent provided better image quality than conventional CTA. Springer Science+Business Media New York, 2015 Computed tomography nationallicence X-ray nationallicence Upper abdomen nationallicence CT angiography nationallicence Xin Lei Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Yang Xiaotang Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Huang Ning GE Healthcare, Beijing, China aut Du Xiaosong Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Zhang Jianxin Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Wang Yanyan Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Hou Lina Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut Gao Jinfang Shanxi Academy of Medical Sciences & Shanxi Dayi Hospital, Taiyuan, China aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2894-2899 0942-8925 40:7<2894 2015 40 261 https://doi.org/10.1007/s00261-015-0462-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0462-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Xin Lei Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Yang Xiaotang Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Huang Ning GE Healthcare, Beijing, China aut NATIONALLICENCE 700 1- Du Xiaosong Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Zhang Jianxin Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Wang Yanyan Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Hou Lina Shanxi Province Tumor Hospital (The Affiliated Tumor Hospital of Shanxi Medical University), Taiyuan, China aut NATIONALLICENCE 700 1- Gao Jinfang Shanxi Academy of Medical Sciences & Shanxi Dayi Hospital, Taiyuan, China aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2894-2899 0942-8925 40:7<2894 2015 40 261