Lowering radiation dose during dedicated colorectal cancer MDCT: comparison of low tube voltage and sinogram-affirmed iterative reconstruction at 80kVp versus blended dual-energy images in a population of patients with low body mass index
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| 024 | 7 | 0 | |a 10.1007/s00261-015-0412-1 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0412-1 | ||
| 245 | 0 | 0 | |a Lowering radiation dose during dedicated colorectal cancer MDCT: comparison of low tube voltage and sinogram-affirmed iterative reconstruction at 80kVp versus blended dual-energy images in a population of patients with low body mass index |h [Elektronische Daten] |c [Chiao-Yun Chen, Jui-Sheng Hsu, Twei-Shiun Jaw, Yu-Ting Kuo, Deng-Chyang Wu, Chien-Hung Lee, Ming-Chen Shih, Tzu-Hsueh Tsai, Chao-Hung Kuo, Yi-Ting Chen, Li-Hwa Yang, Gin-Chung Liu] |
| 520 | 3 | |a Purpose: To assess the diagnostic accuracy, cancer staging, image quality, and radiation dose of 80-kVp computed tomography (CT) images for patients with colorectal cancers (CRCs) using sinogram-affirmed iterative reconstruction (SAFIRE). Methods: Sixty-four consecutive patients (mean weight 62.5 ± 11.3kg, mean BMI 24.1 ± 3.3kg/m2) with known CRC underwent dual-energy CT. Data were reconstructed as a weighted average (WA) 120-kVp dataset. Both filtered back projection (FBP) and SAFIRE were applied to reconstruct the WA 120-Kvp (Protocol A, B) and 80-kVp (Protocol C, D) image sets. The image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) of the cancers, the normal reference tissues, and the effective dose for each protocol were assessed. The cancer detection, staging, and image quality were evaluated. Analysis of variance was used for statistical analysis. Results: Compared with the FBP datasets at WA 120-kVp (Protocol A) and 80-kVp (Protocol C), the SAFIRE-reconstructed images (Protocols B, D) demonstrated significantly lower image noise (P < 0.0083). Protocol D yielded significantly higher CNRs and SNRs for the CRCs and normal reference tissues than did Protocols A and C (P < 0.0083). Protocol D also exhibited a significantly higher CNR for the CRC and some normal reference tissues than did Protocol B (P < 0.0083). For hypovascular liver metastases (n = 10), Protocol D yielded better SNRs and significantly higher CNRs than did Protocol A (P < 0.0083). Overall, accuracy for tumor staging and liver metastasis was 95.3% (61/64) and 100%, respectively, in all of the 4 protocols. The mean effective dose decreased 41% from the WA 120-kVp to the 80-kVp protocols (6.23 vs. 3.68mSv). Conclusions: The 80-kVp technique with SAFIRE provided high SNR, high CNR, and good accuracy for staging in nonobese patients with CRC. Our study results should be extrapolated to patient populations with a high BMI with caution. Further studies of high BMI patients are therefore warranted. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Dual-energy CT |2 nationallicence | |
| 690 | 7 | |a Colorectal cancer |2 nationallicence | |
| 690 | 7 | |a Low-radiation-dose technique |2 nationallicence | |
| 690 | 7 | |a Sinogram-affirmed iterative reconstruction (SAFIRE) |2 nationallicence | |
| 690 | 7 | |a Filtered back projection (FBP) |2 nationallicence | |
| 690 | 7 | |a Abdomen |2 nationallicence | |
| 700 | 1 | |a Chen |D Chiao-Yun |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Hsu |D Jui-Sheng |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Jaw |D Twei-Shiun |u Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Kuo |D Yu-Ting |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Wu |D Deng-Chyang |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Lee |D Chien-Hung |u Department of Public Health, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Shih |D Ming-Chen |u Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Tsai |D Tzu-Hsueh |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Kuo |D Chao-Hung |u Department of Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Chen |D Yi-Ting |u Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Yang |D Li-Hwa |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | |
| 700 | 1 | |a Liu |D Gin-Chung |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/7(2015-10-01), 2867-2876 |x 0942-8925 |q 40:7<2867 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0412-1 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0412-1 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chen |D Chiao-Yun |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Hsu |D Jui-Sheng |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Jaw |D Twei-Shiun |u Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuo |D Yu-Ting |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wu |D Deng-Chyang |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Chien-Hung |u Department of Public Health, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shih |D Ming-Chen |u Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tsai |D Tzu-Hsueh |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuo |D Chao-Hung |u Department of Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chen |D Yi-Ting |u Department of Pathology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yang |D Li-Hwa |u Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Liu |D Gin-Chung |u Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/7(2015-10-01), 2867-2876 |x 0942-8925 |q 40:7<2867 |1 2015 |2 40 |o 261 | ||