caa a22 4500 605493863 CHVBK 20210128100523.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0447-3 doi (NATIONALLICENCE)springer-10.1007/s00261-015-0447-3 Simultaneous Multislice Accelerated Free-Breathing Diffusion-Weighted Imaging of the Liver at 3T [Elektronische Daten] [Chika Obele, Christopher Glielmi, Justin Ream, Ankur Doshi, Naomi Campbell, Hoi Zhang, James Babb, Himanshu Bhat, Hersh Chandarana] Purpose: To perform image quality comparison between accelerated multiband diffusion acquisition (mb2-DWI) and conventional diffusion acquisition (c-DWI) in patients undergoing clinically indicated liver MRI. Methods: In this prospective study 22 consecutive patients undergoing clinically indicated liver MRI on a 3-T scanner equipped to perform multiband diffusion-weighed imaging (mb-DWI) were included. DWI was performed with single-shot spin-echo echo-planar technique with fat-suppression in free breathing with matching parameters when possible using c-DWI, mb-DWI, and multiband DWI with a twofold acceleration (mb2-DWI). These diffusion sequences were compared with respect to various parameters of image quality, lesion detectability, and liver ADC measurements. Results: Accelerated mb2-DWI was 40.9% faster than c-DWI (88 vs. 149s). Various image quality parameter scores were similar or higher on mb2-DWI when compared to c-DWI. The overall image quality score (averaged over the three readers) was significantly higher for mb-2 compared to c-DWI for b=0s/mm2 (3.48±0.52 vs. 3.21±0.54; p=0.001) and for b=800s/mm2 (3.24±0.76 vs. 3.06±0.86; p=0.010). Total of 25 hepatic lesions were visible on mb2-DWI and c-DWI, with identical lesion detectability. There was no significant difference in liver ADC between mb2-DWI and c-DWI (p=0.12). Bland-Altman plot demonstrates lower mean liver ADC with mb2-DWI compared to c-DWI (by 0.043×10−3mm2/s or 3.7% of the average ADC). Conclusion: Multiband technique can be used to increase acquisition speed nearly twofold for free-breathing DWI of the liver with similar or improved overall image quality and similar lesion detectability compared to conventional DWI. Springer Science+Business Media New York, 2015 Liver MRI nationallicence Diffusion-weighted imaging nationallicence Simultaneous multislice acceleration DWI nationallicence Multiband DWI nationallicence Obele Chika Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Glielmi Christopher Siemens HealthCare, New York, NY, USA aut Ream Justin Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Doshi Ankur Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Campbell Naomi Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Zhang Hoi Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Babb James Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Bhat Himanshu Siemens HealthCare, Charlestown, MA, USA aut Chandarana Hersh Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2323-2330 0942-8925 40:7<2323 2015 40 261 https://doi.org/10.1007/s00261-015-0447-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0447-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Obele Chika Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Glielmi Christopher Siemens HealthCare, New York, NY, USA aut NATIONALLICENCE 700 1- Ream Justin Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Doshi Ankur Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Campbell Naomi Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Zhang Hoi Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Babb James Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Bhat Himanshu Siemens HealthCare, Charlestown, MA, USA aut NATIONALLICENCE 700 1- Chandarana Hersh Department of Radiology, New York University Langone Medical Center, 660 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/7(2015-10-01), 2323-2330 0942-8925 40:7<2323 2015 40 261