caa a22 4500 60549388X CHVBK 20210128100523.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00261-014-0326-3 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0326-3 A case of undifferentiated carcinoma of the pancreas mimicking main-duct intraductal papillary mucinous neoplasm (IPMN) [Elektronische Daten] [Yuichi Kawai, Rei Nakamichi, Noriko Kamata, Hideo Miyake, Masahiko Fujino, Shigeki Itoh] We report here a rare case of undifferentiated carcinoma of the pancreas mimicking main-duct intraductal papillary mucinous neoplasm. In an 80-year-old woman, an approximately 8-mm papillary mass was incidentally detected at the downstream edge of a dilatated main pancreatic duct lumen on CT and MRI. Main pancreatic duct dilatation in the pancreatic body and tail and parenchymal atrophy were observed in the upstream of the mass. Histopathologically, the tumor protruded into the downstream edge of the dilatated main pancreatic duct lumen in the pancreatic body. The tumor cells had highly atypical nuclei and abundant polymorphic structures, and showed positive staining for granulocyte colony-stimulating factor, which led to the diagnosis of undifferentiated carcinoma. A total of 13 cases of undifferentiated carcinoma with intraductal tumor growth have been reported to date. The case report by Bergmann et al. has been the smallest in histopathological specimen, and the present case is the smallest in size detected by radiological images. Since early undifferentiated carcinoma of the pancreas can resemble those of main-duct intraductal papillary mucinous neoplasm in cross-sectional images, we have to consider undifferentiated carcinoma in the differential diagnosis of the solitary and papillary mass with low contrast enhancement in early phase in the main pancreatic duct. The Author(s), 2014 Undifferentiated carcinoma of the pancreas nationallicence Main-duct intraductal papillary mucinous neoplasm nationallicence Intraductal tumor growth nationallicence Main pancreatic duct dilatation nationallicence Kawai Yuichi Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut Nakamichi Rei Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut Kamata Noriko Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut Miyake Hideo General and Gastroenterological Surgery, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan aut Fujino Masahiko Department of Pathology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan aut Itoh Shigeki Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 466-470 0942-8925 40:3<466 2015 40 261 https://doi.org/10.1007/s00261-014-0326-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0326-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kawai Yuichi Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut NATIONALLICENCE 700 1- Nakamichi Rei Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut NATIONALLICENCE 700 1- Kamata Noriko Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut NATIONALLICENCE 700 1- Miyake Hideo General and Gastroenterological Surgery, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan aut NATIONALLICENCE 700 1- Fujino Masahiko Department of Pathology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan aut NATIONALLICENCE 700 1- Itoh Shigeki Department of Diagnostic Radiology, Japanese Red Cross Nagoya Daiichi Hospital, 3-35 Michishita-cho, Nakamura-ku, 453-8511, Nagoya, Aichi, Japan aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 466-470 0942-8925 40:3<466 2015 40 261