Hepatobiliary agents and their role in LI-RADS

Verfasser / Beitragende:
[Thomas Hope, Kathryn Fowler, Claude Sirlin, Eduardo Costa, Judy Yee, Benjamin Yeh, Jay Heiken]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/3(2015-03-01), 613-625
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0227-5  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0227-5 
245 0 0 |a Hepatobiliary agents and their role in LI-RADS  |h [Elektronische Daten]  |c [Thomas Hope, Kathryn Fowler, Claude Sirlin, Eduardo Costa, Judy Yee, Benjamin Yeh, Jay Heiken] 
520 3 |a The Liver Imaging Reporting and Data System (LI-RADS) was introduced with the goal of standardizing the diagnosis of hepatocellular carcinoma. The 2014 version of LI-RADS incorporates the use of hepatobiliary contrast agents (HBAs) into the diagnostic algorithm, including gadoxetate disodium and gadobenate dimeglumine. Three new ancillary features are introduced: hepatobiliary phase (HBP) hypointensity and HBP hypointense rim favor malignancy, while HBP isointensity favors benignity. HBP hyperintensity favors neither malignancy nor benignity. In this review, we describe how to use these new features as well as numerous pitfalls associated with the use ofHBAs, including hemangiomas, cholangiocarcinomas, and focal confluent fibrosis. Importantly, findings on the HBP are not included as major criteria and therefore the criteria for the diagnosis of LI-RADS 5 observations remain unchanged, and so congruence with the Organ Procurement Transplant Network system remains intact. Additionally, we review how the major features in LI-RADS, arterial phase hyperenhancement, threshold growth, and washout and capsule appearance, may be affected with HBAs. Notably with HBAs, hypointensity on the delayed phase, termed the transitional phase, does not qualify as washout appearance due to the possibility of early parenchymal enhancement. It is hoped that the incorporation of HBAs into LI-RADS will help create consistency when interpreting HBA enhanced MRIs. 
540 |a Springer Science+Business Media New York (outside the USA), 2014 
690 7 |a Hepatocellular carcinoma  |2 nationallicence 
690 7 |a Hepatobiliary agents  |2 nationallicence 
690 7 |a Liver  |2 nationallicence 
690 7 |a LI-RADS  |2 nationallicence 
690 7 |a Gadoxetate  |2 nationallicence 
690 7 |a Gadobenate dimeglumine  |2 nationallicence 
700 1 |a Hope  |D Thomas  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
700 1 |a Fowler  |D Kathryn  |u Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA  |4 aut 
700 1 |a Sirlin  |D Claude  |u Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, USA  |4 aut 
700 1 |a Costa  |D Eduardo  |u Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, USA  |4 aut 
700 1 |a Yee  |D Judy  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
700 1 |a Yeh  |D Benjamin  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
700 1 |a Heiken  |D Jay  |u Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 613-625  |x 0942-8925  |q 40:3<613  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0227-5  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a review-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0227-5  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Hope  |D Thomas  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fowler  |D Kathryn  |u Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sirlin  |D Claude  |u Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Costa  |D Eduardo  |u Liver Imaging Group, Department of Radiology, University of California San Diego, San Diego, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yee  |D Judy  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yeh  |D Benjamin  |u Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue - 0628, 94143-0628, San Francisco, CA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Heiken  |D Jay  |u Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 613-625  |x 0942-8925  |q 40:3<613  |1 2015  |2 40  |o 261