caa a22 4500 605493979 CHVBK 20210128100523.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00261-014-0235-5 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0235-5 Diffusion-weighted magnetic resonance imaging for non-neoplastic conditions in the hepatobiliary and pancreatic regions: pearls and potential pitfalls in imaging interpretation [Elektronische Daten] [Nam Lee, Suk Kim, Dong Kim, Hyung Seo, Hyun Kim, Hong Jo, Tae Kim] Potentially, diffusion-weighted magnetic resonance imaging (DWI) can assess the functional information on concerning the status of tissue cellularity, because increased cellularity is associated with impeded diffusion. DWI in the hepatobiliary and pancreatic regions has demonstrated the usefulness to detect malignant lesions and differentiate them from benign lesions. However, it has been shown more recently that there is some overlap in ADC values for benign and malignant neoplasms. Moreover, some non-neoplastic lesions in the hepatobiliary and pancreatic regions exhibit restricted diffusion on DWI, because of pus, inflammation, or high cellularity. Focal eosinophilic liver disease, hepatic inflammatory myofibroblastic tumor, granulomatous liver disease, acute cholecystitis, xanthogranulomatous cholecystitis, focal pancreatitis, or autoimmune pancreatitis frequently exhibit restricted diffusion on DWI, which may be confused with malignancy in the hepatobiliary and pancreatic regions. Thus, DWI should not be interpreted in isolation, but in conjunction with other conventional images, to avoid the diagnostic pitfalls of DWI. Nevertheless, the presence of diffusion restriction in the non-neoplastic lesions sometimes provides additional information regarding the diagnosis, in problematic patients where conventional images have yielded equivocal findings. DWI may help differentiate hepatic abscess from malignant necrotic tumors, gallbladder empyema from dense bile or sludge in the gallbladder, and pylephlebitis from bland thrombosis in the portal vein. Therefore, knowledge of DWI findings to conventional imaging findings of diffusion-restricted non-neoplastic conditions in the hepatobiliary and pancreatic regions helps establishing a correct diagnosis. Springer Science+Business Media New York, 2014 Diffusion-weighted magnetic resonance imaging nationallicence Liver diseases nationallicence Bile tract diseases nationallicence Pancreatic diseases nationallicence Lee Nam Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, #179, Gudeok-Ro, Seo-Gu, 602-739, Busan, Republic of Korea aut Kim Suk Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, #179, Gudeok-Ro, Seo-Gu, 602-739, Busan, Republic of Korea aut Kim Dong Department of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut Seo Hyung Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut Kim Hyun Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut Jo Hong Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut Kim Tae Department of Radiology, Yangsan Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 626-770, Yangsan, Republic of Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 643-662 0942-8925 40:3<643 2015 40 261 https://doi.org/10.1007/s00261-014-0235-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0235-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lee Nam Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, #179, Gudeok-Ro, Seo-Gu, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Kim Suk Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, #179, Gudeok-Ro, Seo-Gu, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Kim Dong Department of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Seo Hyung Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Kim Hyun Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Jo Hong Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 602-739, Busan, Republic of Korea aut NATIONALLICENCE 700 1- Kim Tae Department of Radiology, Yangsan Pusan National University Hospital, Pusan National University School of Medicine, Pusan National University, 626-770, Yangsan, Republic of Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 643-662 0942-8925 40:3<643 2015 40 261