caa a22 4500 605493987 CHVBK 20210128100523.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00261-014-0229-3 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0229-3 CT and MR imaging findings of hepatic epithelioid hemangioendotheliomas: emphasis on single nodular type [Elektronische Daten] [Eu Kim, Sung Rha, Young Lee, Ie Yoo, Eun Jung, Jae Byun] Purpose: To evaluate imaging findings of hepatic epithelioid hemangioendothelioma (HEH), with emphasis on solitary form at theinitial presentation. Materials and methods: Ten cases of pathologically confirmed HEH were retrospectively reviewed; seven patients had CT and MR images and three had only CT images. Two radiologists assessed the followings in consensus: lesion number, size, location, presence of capsular retraction and calcification, attenuation, signal intensity, and enhancement pattern. Results: Initially, HEHs manifested as a single mass (n=5) or multiple masses (n=5). One case demonstrated a solitary nodule at first, which subsequently transformed to multifocal nodules on serial follow-up. The maximal diameter of the lesions ranged from 1.8 to 10cm (mean 4.2cm). All cases showed predominant subcapsular location. Capsular retraction was seen in multinodular types, but not in solitary types. Two patients had intra-lesional calcifications. HEHs showed minimal enhancement (7/7 patients) on the hepatic arterial phase CT and rim-like enhancement (5/10 patients), minimal enhancement (2/10 patients), multilayered target enhancement (2/10 patients), and peripheral nodular enhancement (1/10 patients) on the portal venous phase CT. On MR images (n=7), HEHs showed hypointensity on T1-weighted images and hyperintensity on T2-weighted images. Dynamic contrast-enhanced MR images revealed progressive centripetal fill-in enhancement (7/7 patients). On Gd-EOB-DTPA-enhanced hepatobiliary phase images, HEH manifested as homogeneous hypointensity (3/5 patients) and target-shaped hypointensity (2/5 patients). Conclusion: HEH can manifest as single nodular, multinodular, or diffuse type. Common imaging features of HEH are multiple subcapsular nodules with coalescence, capsular retraction, peripheral, and delayed enhancement. However, HEH can manifest as a solitary subcapsular mass with minimal or rim-like enhancement at early phase and progressive centripetal fill-in enhancement during dynamic phase imaging, representing early stage of HEH. A single nodular type can progress to multifocal nodular type during follow-up. Springer Science+Business Media New York, 2014 CT nationallicence Hepatic epithelioid hemangioendothelioma nationallicence Liver nationallicence MRI nationallicence PET/CT nationallicence Kim Eu Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut Rha Sung Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut Lee Young Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut Yoo Ie Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut Jung Eun Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea aut Byun Jae Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 500-509 0942-8925 40:3<500 2015 40 261 https://doi.org/10.1007/s00261-014-0229-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0229-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kim Eu Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut NATIONALLICENCE 700 1- Rha Sung Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut NATIONALLICENCE 700 1- Lee Young Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut NATIONALLICENCE 700 1- Yoo Ie Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut NATIONALLICENCE 700 1- Jung Eun Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea aut NATIONALLICENCE 700 1- Byun Jae Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, 137-701, Seoul, Republic of Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 500-509 0942-8925 40:3<500 2015 40 261