A case of gastric-type adenocarcinoma of the uterine cervix associated with lobular endocervical glandular hyperplasia: radiologic-pathologic correlation

Verfasser / Beitragende:
[Takahiro Tsuboyama, Kazuhiro Yamamoto, Go Nakai, Takashi Yamada, Satoe Fujiwara, Yoshito Terai, Masahide Ohmichi, Yoshifumi Narumi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/3(2015-03-01), 459-465
Format:
Artikel (online)
ID: 605494002
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024 7 0 |a 10.1007/s00261-014-0323-6  |2 doi 
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245 0 2 |a A case of gastric-type adenocarcinoma of the uterine cervix associated with lobular endocervical glandular hyperplasia: radiologic-pathologic correlation  |h [Elektronische Daten]  |c [Takahiro Tsuboyama, Kazuhiro Yamamoto, Go Nakai, Takashi Yamada, Satoe Fujiwara, Yoshito Terai, Masahide Ohmichi, Yoshifumi Narumi] 
520 3 |a Gastric-type adenocarcinoma (GAS) of the uterine cervix is a recently defined subtype of mucinous adenocarcinoma. GAS is proposed to include minimal deviation adenocarcinoma (MDA) as a very well-differentiated form and has been suggested to arise from lobular endocervical glandular hyperplasia (LEGH). We report the magnetic resonance imaging (MRI) findings of a GAS associated with LEGH. On MRI, the LEGH component was detected as multiple cystic lesions arranged in a "cosmos pattern”, while the GAS was depicted as a predominantly solid lesion containing obvious adenocarcinoma and MDA components, which appeared as mass-like and infiltrative components, respectively. The GAS exhibited tiny cysts on three-dimensional T2-weighted images, high intensity on diffusion-weighted images mostly due to T2 shine-through effect according to apparent diffusion coefficient (ADC) map, and reticular enhancement on dynamic contrast-enhanced MRI, which reflected numerous dilated glandular structures of the tumor. Low ADC was only observed at the deepest invasion front of the obvious adenocarcinoma component. Our case suggests that the MRI features of GAS vary depending on the tumor's histological components, and it is important to be aware of these imaging features when evaluating LEGH on MRI. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Uterine cervix  |2 nationallicence 
690 7 |a Gastric-type adenocarcinoma  |2 nationallicence 
690 7 |a MDA  |2 nationallicence 
690 7 |a LEGH  |2 nationallicence 
690 7 |a MRI  |2 nationallicence 
700 1 |a Tsuboyama  |D Takahiro  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Yamamoto  |D Kazuhiro  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Nakai  |D Go  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Yamada  |D Takashi  |u Department of Pathology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Fujiwara  |D Satoe  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Terai  |D Yoshito  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Ohmichi  |D Masahide  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
700 1 |a Narumi  |D Yoshifumi  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 459-465  |x 0942-8925  |q 40:3<459  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0323-6  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0323-6  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tsuboyama  |D Takahiro  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yamamoto  |D Kazuhiro  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nakai  |D Go  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yamada  |D Takashi  |u Department of Pathology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Fujiwara  |D Satoe  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Terai  |D Yoshito  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ohmichi  |D Masahide  |u Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Narumi  |D Yoshifumi  |u Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, 569-8686, Takatsuki, Osaka, Japan  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 459-465  |x 0942-8925  |q 40:3<459  |1 2015  |2 40  |o 261