Comparison of re-biopsy with preceded MRI and re-biopsy without preceded MRI in patients with previous negative biopsy and persistently high PSA

Verfasser / Beitragende:
[Byung Park, Seong Jeon, Bumsoo Park, Jung Park, Chan Kim, Hyun Lee, Han Choi]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/3(2015-03-01), 571-577
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0245-3  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0245-3 
245 0 0 |a Comparison of re-biopsy with preceded MRI and re-biopsy without preceded MRI in patients with previous negative biopsy and persistently high PSA  |h [Elektronische Daten]  |c [Byung Park, Seong Jeon, Bumsoo Park, Jung Park, Chan Kim, Hyun Lee, Han Choi] 
520 3 |a Purpose: To retrospectively compare re-biopsy with preceded magnetic resonance imaging (MRI) and re-biopsy without preceded MRI. Materials and methods: Between January 2007 and May 2011, 669 patients (mean 64years; range 38-91years) underwent a re-biopsy because of previous negative biopsy (median 1; 1-5) and persistently high prostate-specific antigen (PSA 10.6ng/ml; 2.5-997.1ng/ml). 3T MRI using a phased-array coil was performed in 171 (MRI group) but not in 498 (non-MRI group) prior to re-biopsy. Transrectal ultrasound-guided biopsy was performed in both MRI and non-MRI groups. MRI and non-MRI groups were compared in terms of cancer detection rate [(number of cancer-proven patients/number of patients in MRI or non-MRI group)×100] and positive core rate [(number of cancer-positive cores/number of cores in MRI or non-MRI group)×100] using Fisher exact test. Odds ratio and 95% confidence interval were also obtained. Pathologic diagnosis of the biopsy was considered standard reference. Results: Of 669 patients, 129 (19.3%) were diagnosed with adenocarcinoma. The cancer detection rates of MRI and non-MRI groups were 33.3% (57/171) and 14.5% (72/498), respectively (p<0.001). The positive core rates of these groups were 9.2% (167/1818) and 3.2% (179/5631), respectively (p<0.001). The odd ratios of cancer detection rate and positive core rate were 3.0 (95% confidence interval 2.0-4.4) and 3.1 (2.5-3.8), respectively. Conclusion: Re-biopsy with preceded MRI yields higher cancer detection rate and positive core rate than re-biopsy without preceded MRI. MRI should be considered prior to re-biopsy in patients with previous negative biopsy and persistently high PSA. 
540 |a Springer Science+Business Media New York, 2014 
700 1 |a Park  |D Byung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
700 1 |a Jeon  |D Seong  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Park  |D Bumsoo  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Park  |D Jung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
700 1 |a Kim  |D Chan  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
700 1 |a Lee  |D Hyun  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Choi  |D Han  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 571-577  |x 0942-8925  |q 40:3<571  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0245-3  |q text/html  |z Onlinezugriff via DOI 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Byung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Jeon  |D Seong  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Bumsoo  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Jung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Chan  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lee  |D Hyun  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Choi  |D Han  |u The Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 571-577  |x 0942-8925  |q 40:3<571  |1 2015  |2 40  |o 261