Differentiation of lipid poor angiomyolipoma from hepatocellular carcinoma on gadoxetic acid-enhanced liver MR imaging
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| 024 | 7 | 0 | |a 10.1007/s00261-014-0244-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-014-0244-4 | ||
| 245 | 0 | 0 | |a Differentiation of lipid poor angiomyolipoma from hepatocellular carcinoma on gadoxetic acid-enhanced liver MR imaging |h [Elektronische Daten] |c [Rihyeon Kim, Jeong Lee, Ijin Joo, Dong Lee, Sungmin Woo, Joon Han, Byung Choi] |
| 520 | 3 | |a Purpose: To investigate magnetic resonance (MR) findings of angiomyolipoma (AML) on gadoxetic acid-enhanced MR imaging, and to identify features that differentiate AML from hepatocellular carcinoma (HCC) in patients with a low risk of HCC development. Methods: This retrospective study was institutional review board approved, and the requirement for informed consent was waived. Twelve patients with hepatic AML who underwent gadoxetic acid-enhanced MRI with no risk factors for HCC development were recruited. Twenty-seven patients with HCC under the same inclusion criteria were recruited as control. Two radiologists analyzed the images in consensus for morphologic features, enhancement patterns, and hepatobiliary phase (HBP) findings. All results were analyzed using the Mann-Whitney test, two-tailed Fisher exact test, and chi-square test. Results: Patients with AML were younger than those with HCC (48.8±15years for AML vs. 62.7±14.2years for HCC, p=0.008) with female predominance, while most HCC patients were male (75% (9/12) vs. 15% (4/27), p<0.001). The most prevalent enhancement pattern was arterial enhancement followed by hypointensity at portal or transitional phases for both AMLs (58% (7/12)) and HCCs (74% (20/27)) (p=0.455). However, during the HBP, AMLs frequently showed more homogeneous hypointensity than HCCs (83% (10/12) vs. 41% (11/27), p=0.018). When compared with the signal intensity of the spleen, the mean relative signal intensity of the AML was 91.2±15.4%, while in HCCs, it was 128.7±40% (p<0.001). Conclusions: Although AMLs showed similar enhancement patterns to HCCs during the dynamic phases of gadoxetic acid-enhanced MRI, using characteristic MR features of AML during the HBP and demographic differences, one can better differentiate AML from HCC. | |
| 540 | |a Springer Science+Business Media New York, 2014 | ||
| 690 | 7 | |a Hepatic angiomyolipoma |2 nationallicence | |
| 690 | 7 | |a Hepatocellular carcinoma |2 nationallicence | |
| 690 | 7 | |a Gadoxetic acid-enhanced MR |2 nationallicence | |
| 690 | 7 | |a Hepatobiliary phase |2 nationallicence | |
| 700 | 1 | |a Kim |D Rihyeon |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Lee |D Jeong |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Joo |D Ijin |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Lee |D Dong |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Woo |D Sungmin |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Han |D Joon |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Choi |D Byung |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/3(2015-03-01), 531-541 |x 0942-8925 |q 40:3<531 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-014-0244-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-014-0244-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kim |D Rihyeon |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Jeong |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Joo |D Ijin |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Dong |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Woo |D Sungmin |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Han |D Joon |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Choi |D Byung |u Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-Gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/3(2015-03-01), 531-541 |x 0942-8925 |q 40:3<531 |1 2015 |2 40 |o 261 | ||