caa a22 4500 605494061 CHVBK 20210128100524.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00261-014-0236-4 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0236-4 Imaging patterns of intraductal papillary mucinous neoplasms of the pancreas: An illustrated discussion of the International Consensus Guidelines for the Management of IPMN [Elektronische Daten] [Naomi Campbell, Seth Katz, Joanna Escalon, Richard Do] Intraductal papillary mucinous neoplasms (IPMN) are being diagnosed with increasing frequency, necessitating an algorithm to help stratify patients into low- and high-risk groups, for follow-up versus more invasive evaluation. New evidence concerning their natural history and overall risk of malignancy has emerged since the 2006 International Association of Pancreatology consensus guidelines, prompting an update in 2012, that distinguishes radiologic ‘worrisome features' from ‘high-risk stigmata'. The aim of this article is to illustrate, with case examples, the variable imaging patterns of IPMN and how their radiologic features, such as cyst size and mural nodules, are interpreted in the context of the new 2012 guidelines. The 2012 and 2006 guidelines will be compared and discussed with reference to additional studies that have since been published. Despite these guidelines, lingering uncertainty remains about the natural history of IPMN, a source of unease to both radiologists and referring clinicians alike, mandating further refinement of clinical and radiologic parameters predictive of malignancy. Emerging data regarding the risk of extrapancreatic malignancy, as well as synchronous or metachronous pancreatic ductal adenocarcinoma remote in location from a branch duct IPMN are also reviewed. With the expanding research and evolving understanding of this clinicopathologic entity across the globe, radiologists will continue to play an important role in the management of patients with IPMN. Springer Science+Business Media New York, 2014 IPMN nationallicence Intraductal papillary mucinous neoplasm of the pancreas nationallicence Pancreatic cystic lesion nationallicence Pancreatic cancer nationallicence Pancreatic neoplasm nationallicence Campbell Naomi Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut Katz Seth Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut Escalon Joanna Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut Do Richard Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 663-677 0942-8925 40:3<663 2015 40 261 https://doi.org/10.1007/s00261-014-0236-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0236-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Campbell Naomi Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut NATIONALLICENCE 700 1- Katz Seth Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut NATIONALLICENCE 700 1- Escalon Joanna Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut NATIONALLICENCE 700 1- Do Richard Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, 10065, New York, NY, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 663-677 0942-8925 40:3<663 2015 40 261