T2-weighted imaging of the prostate: Impact of the BLADE technique on image quality and tumor assessment

Verfasser / Beitragende:
[Andrew Rosenkrantz, Genevieve Bennett, Ankur Doshi, Fang-Ming Deng, James Babb, Samir Taneja]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/3(2015-03-01), 552-559
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0225-7  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0225-7 
245 0 0 |a T2-weighted imaging of the prostate: Impact of the BLADE technique on image quality and tumor assessment  |h [Elektronische Daten]  |c [Andrew Rosenkrantz, Genevieve Bennett, Ankur Doshi, Fang-Ming Deng, James Babb, Samir Taneja] 
520 3 |a Purpose: To retrospectively compare standard and BLADE T2-weighted imaging (T2WI) sequences of the prostate in terms of image quality and tumor assessment. Methods: 49 prostate cancer patients (64±6years) who underwent 3T phased-array coil MRI before prostatectomy were included. T2WI was acquired using standard rectilinear and BLADE techniques. Two readers (R1, R2) independently localized the dominant lesion using T2WI alone and using multi-parametric imaging; recorded presence of extraprostatic extension (EPE) in each lobe; and scored lesion conspicuity and absence of motion artifact (1-5 scale; 5=highest quality). A third reader, unblinded to pathology, placed ROIs to record tumor-to-peripheral-zone contrast. Standard and BLADE T2WI were compared using paired Wilcoxon tests. Results: BLADE showed a trend toward improved motion artifact for R1 (3.4±1.3 vs. 2.9±1.5; p=0.054) but not R2 (4.0±1.0 vs. 3.9±1.1; p=0.880). Dominant lesions showed significantly lower conspicuity using BLADE for R1 (2.8±2.0 vs. 3.2±2.0; p=0.011) but not R2 (2.3±1.6 vs. 2.4±1.7; p=0.353), and significantly lower tumor-to-peripheral-zone contrast using BLADE (0.35±0.13 vs. 0.42±0.15; p≤0.001). R1 and R2 correctly localized four and three fewer dominant tumors, respectively, using BLADE than standard T2WI, although both correctly localized a similar fraction of dominant tumors using multi-parametric sequences. While R1 detected EPE in 10 of 11 patients using both sequences, R2 detected EPE in 3 more patients using BLADE. Conclusion: BLADE may help reduce motion artifact of prostate T2WI and assist EPE detection, although at expense of reduced image contrast. In practice, BLADE may be useful in patients in whom initial T2WI is degraded by motion. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Prostate cancer  |2 nationallicence 
690 7 |a MRI  |2 nationallicence 
690 7 |a T2-weighted imaging  |2 nationallicence 
690 7 |a Motion artifact  |2 nationallicence 
700 1 |a Rosenkrantz  |D Andrew  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Bennett  |D Genevieve  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Doshi  |D Ankur  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Deng  |D Fang-Ming  |u Department of Pathology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Babb  |D James  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
700 1 |a Taneja  |D Samir  |u Division of Urologic Oncology, Department of Urology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rosenkrantz  |D Andrew  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bennett  |D Genevieve  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Doshi  |D Ankur  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Deng  |D Fang-Ming  |u Department of Pathology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Babb  |D James  |u Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Taneja  |D Samir  |u Division of Urologic Oncology, Department of Urology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/3(2015-03-01), 552-559  |x 0942-8925  |q 40:3<552  |1 2015  |2 40  |o 261