caa a22 4500 60549407X CHVBK 20210128100524.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s00261-014-0225-7 doi (NATIONALLICENCE)springer-10.1007/s00261-014-0225-7 T2-weighted imaging of the prostate: Impact of the BLADE technique on image quality and tumor assessment [Elektronische Daten] [Andrew Rosenkrantz, Genevieve Bennett, Ankur Doshi, Fang-Ming Deng, James Babb, Samir Taneja] Purpose: To retrospectively compare standard and BLADE T2-weighted imaging (T2WI) sequences of the prostate in terms of image quality and tumor assessment. Methods: 49 prostate cancer patients (64±6years) who underwent 3T phased-array coil MRI before prostatectomy were included. T2WI was acquired using standard rectilinear and BLADE techniques. Two readers (R1, R2) independently localized the dominant lesion using T2WI alone and using multi-parametric imaging; recorded presence of extraprostatic extension (EPE) in each lobe; and scored lesion conspicuity and absence of motion artifact (1-5 scale; 5=highest quality). A third reader, unblinded to pathology, placed ROIs to record tumor-to-peripheral-zone contrast. Standard and BLADE T2WI were compared using paired Wilcoxon tests. Results: BLADE showed a trend toward improved motion artifact for R1 (3.4±1.3 vs. 2.9±1.5; p=0.054) but not R2 (4.0±1.0 vs. 3.9±1.1; p=0.880). Dominant lesions showed significantly lower conspicuity using BLADE for R1 (2.8±2.0 vs. 3.2±2.0; p=0.011) but not R2 (2.3±1.6 vs. 2.4±1.7; p=0.353), and significantly lower tumor-to-peripheral-zone contrast using BLADE (0.35±0.13 vs. 0.42±0.15; p≤0.001). R1 and R2 correctly localized four and three fewer dominant tumors, respectively, using BLADE than standard T2WI, although both correctly localized a similar fraction of dominant tumors using multi-parametric sequences. While R1 detected EPE in 10 of 11 patients using both sequences, R2 detected EPE in 3 more patients using BLADE. Conclusion: BLADE may help reduce motion artifact of prostate T2WI and assist EPE detection, although at expense of reduced image contrast. In practice, BLADE may be useful in patients in whom initial T2WI is degraded by motion. Springer Science+Business Media New York, 2014 Prostate cancer nationallicence MRI nationallicence T2-weighted imaging nationallicence Motion artifact nationallicence Rosenkrantz Andrew Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Bennett Genevieve Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Doshi Ankur Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Deng Fang-Ming Department of Pathology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Babb James Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Taneja Samir Division of Urologic Oncology, Department of Urology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 552-559 0942-8925 40:3<552 2015 40 261 https://doi.org/10.1007/s00261-014-0225-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0225-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rosenkrantz Andrew Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Bennett Genevieve Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Doshi Ankur Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Deng Fang-Ming Department of Pathology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Babb James Department of Radiology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 700 1- Taneja Samir Division of Urologic Oncology, Department of Urology, NYU Langone Medical Center, 550 First Avenue, 10016, New York, NY, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/3(2015-03-01), 552-559 0942-8925 40:3<552 2015 40 261