caa a22 4500 605494282 CHVBK 20210128100525.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00261-014-0282-y doi (NATIONALLICENCE)springer-10.1007/s00261-014-0282-y Cross-vendor validation of liver magnetic resonance elastography [Elektronische Daten] [Suraj Serai, Meng Yin, Hui Wang, Richard Ehman, Daniel Podberesky] Purpose: To evaluate and validate the reproducibility of MR Elastography (MRE)-derived liver stiffness values on two different MR vendor platforms performed on the same subject on the same day. Methods: This investigation was approved by the hospital IRB. MRE exams were performed twice in identical fashion in eight volunteers and in five clinical patients on two different 1.5T MR scanners—once on a Philips MR scanner and immediately afterward in back-to-back fashion on a General Electric MR scanner, or vice versa. All scan parameters were kept identical on the two platforms to the best extent possible. After the MRE magnitude and phase images were obtained, the data were converted into quantitative images displaying the stiffness of the liver parenchyma. Mean liver stiffness values between the two platforms were compared using interclass correlation with a p value <0.05 considered statistically significant. Results: Interclass correlation coefficient (ICC) value of 0.994 was obtained for 13 subjects with p value <0.001 indicating a significantly positive correlation. Conclusion: As MRE gains in acceptance and as its availability becomes more widespread, it is important to ascertain and confirm that liver stiffness values obtained on different MRE vendor platforms are consistent and reproducible. In this small pilot investigation, we demonstrate that liver stiffness measurement with MRE is reproducible and has very good consistency across two vendor platforms. Springer Science+Business Media New York, 2014 MRE nationallicence Liver elastography nationallicence MRE validation nationallicence Serai Suraj Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA aut Yin Meng Department of Radiology, Mayo Clinic, Rochester, MN, USA aut Wang Hui Philips Healthcare, Cleveland, OH, USA aut Ehman Richard Department of Radiology, Mayo Clinic, Rochester, MN, USA aut Podberesky Daniel Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/4(2015-04-01), 789-794 0942-8925 40:4<789 2015 40 261 https://doi.org/10.1007/s00261-014-0282-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-014-0282-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Serai Suraj Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA aut NATIONALLICENCE 700 1- Yin Meng Department of Radiology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Wang Hui Philips Healthcare, Cleveland, OH, USA aut NATIONALLICENCE 700 1- Ehman Richard Department of Radiology, Mayo Clinic, Rochester, MN, USA aut NATIONALLICENCE 700 1- Podberesky Daniel Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/4(2015-04-01), 789-794 0942-8925 40:4<789 2015 40 261