Prediction of microvascular invasion of hepatocellular carcinoma using gadoxetic acid-enhanced MR and 18F-FDG PET/CT
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| 024 | 7 | 0 | |a 10.1007/s00261-014-0256-0 |2 doi |
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| 245 | 0 | 0 | |a Prediction of microvascular invasion of hepatocellular carcinoma using gadoxetic acid-enhanced MR and 18F-FDG PET/CT |h [Elektronische Daten] |c [Su Ahn, Jeong Lee, Ijin Joo, Eun Lee, Soo Lee, Gi Cheon, Joon Han, Byung Choi] |
| 520 | 3 | |a Purpose: To identify the gadoxetic acid-enhanced MR and the 18F-fludeoxyglucose (FDG) PET/CT findings associated with microvascular invasion (MVI) of hepatocellular carcinoma (HCC) in patients who are undergoing liver transplantation (LT). Methods: Fifty-one patients with 78 HCCs underwent LT. Preoperative MRI and 18F-FDG PET/CT findings were retrospectively analyzed and the association of the imaging findings with MVI was assessed. Results: Univariate analysis revealed that hypointensity seen on T1WI (OR=4.329, p=0.011), peritumoral enhancement (OR=7.000, p=0.008), inhomogeneity on arterial phase (OR=4.321, p=0.011), delayed phase (OR=4.519, p=0.009) or hepatobiliary phase (OR=3.564, p=0.032), and the large tumor size (>5cm) (OR=12.091, p=0.001) showed statistically significant associations with MVI. The ratio of tumor maximum standardized uptake value (SUV) to normal liver mean SUV (TSUVmax/LSUVmean) (2.05±1.43 vs. 1.08±0.37) revealed significantly higher value in the MVI-positive group. Multivariate analysis revealed that peritumoral enhancement and a TSUVmax/LSUVmean of 1.2 or greater had a statistically significant association with MVI, with odds ratios of 10.648 (p=0.016) and 14.218 (p=0.001), respectively. Conclusions: Preoperative imaging findings such as peritumoral enhancement seen on gadoxetic acid-enhanced MR and a TSUVmax/LSUVmean of 1.2 or more on 18F-FDG PET/CT, may suggest the presence of MVI in HCC patients. | |
| 540 | |a Springer Science+Business Media New York, 2014 | ||
| 690 | 7 | |a Hepatocellular carcinoma |2 nationallicence | |
| 690 | 7 | |a Microvascular invasion |2 nationallicence | |
| 690 | 7 | |a Liver transplantation |2 nationallicence | |
| 690 | 7 | |a MRI |2 nationallicence | |
| 690 | 7 | |a PET/CT |2 nationallicence | |
| 700 | 1 | |a Ahn |D Su |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Lee |D Jeong |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Joo |D Ijin |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Lee |D Eun |u Department of Radiology, National Cancer Center, Goyang, Korea |4 aut | |
| 700 | 1 | |a Lee |D Soo |u Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea |4 aut | |
| 700 | 1 | |a Cheon |D Gi |u Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea |4 aut | |
| 700 | 1 | |a Han |D Joon |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | |
| 700 | 1 | |a Choi |D Byung |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/4(2015-04-01), 843-851 |x 0942-8925 |q 40:4<843 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-014-0256-0 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-014-0256-0 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ahn |D Su |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Jeong |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Joo |D Ijin |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Eun |u Department of Radiology, National Cancer Center, Goyang, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lee |D Soo |u Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cheon |D Gi |u Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Han |D Joon |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Choi |D Byung |u Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, 110-744, Seoul, Korea |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/4(2015-04-01), 843-851 |x 0942-8925 |q 40:4<843 |1 2015 |2 40 |o 261 | ||