Magnetic resonance elastography and acoustic radiation force impulse for staging hepatic fibrosis: a meta-analysis

Verfasser / Beitragende:
[Yang Guo, Sudharshan Parthasarathy, Preeya Goyal, Robert McCarthy, Andrew Larson, Frank Miller]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/4(2015-04-01), 818-834
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-014-0137-6  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-014-0137-6 
245 0 0 |a Magnetic resonance elastography and acoustic radiation force impulse for staging hepatic fibrosis: a meta-analysis  |h [Elektronische Daten]  |c [Yang Guo, Sudharshan Parthasarathy, Preeya Goyal, Robert McCarthy, Andrew Larson, Frank Miller] 
520 3 |a Purpose: Elastography is a non-invasive method to quantify fibrosis based on tissue mechanical properties. We performed a meta-analysis to assess the diagnostic accuracy of two such techniques: Acoustic Radiation Force Impulse Imaging (ARFI) or Magnetic Resonance Elastography (MRE) for staging hepatic fibrosis. Materials and Methods: Literature databases were searched until June 2013. Inclusion criteria were evaluation of MRE or ARFI, liver biopsy, and reported sensitivity and specificity. A random effects model was used to combine sensitivity and specificity, from which positive (LR+) and negative (LR−) likelihood ratios, diagnostic odds ratios, and area under receiver operating characteristics curve (AUROC) were derived. Differences between MRE and ARFI were compared with t tests (P<0.05 considered significant). Results: Eleven MRE studies including 982 patients and fifteen ARFI studies including 2,128 patients were selected. AUROC for MRE staging fibrosis were 0.94, 0.97, 0.96, and 0.97 for F1-F4, respectively, whereas AUROC for ARFI staging were 0.82, 0.85, 0.94, and 0.94 for F1-F4, respectively. Significance was found in AUROC between MRE and ARFI for the diagnosis of stage 1 and 2 fibrosis. Conclusion: MRE is more accurate than ARFI with a higher combination of sensitivity, specificity, LR, and AUROC particularly in diagnosing early stages of hepatic fibrosis. 
540 |a Springer Science+Business Media New York, 2014 
690 7 |a Hepatic fibrosis  |2 nationallicence 
690 7 |a Magnetic resonance imaging  |2 nationallicence 
690 7 |a MR elastography  |2 nationallicence 
690 7 |a Acoustic radiation force impulse  |2 nationallicence 
690 7 |a Meta-analysis  |2 nationallicence 
690 7 |a APRI : Aspartate aminotransferase-to-platelet ratio index  |2 nationallicence 
690 7 |a ARFI : Acoustic radiation force impulse  |2 nationallicence 
690 7 |a AUROC : Area under the receiver operating characteristic curve  |2 nationallicence 
690 7 |a ALD : Alcoholic liver disease  |2 nationallicence 
690 7 |a AIH : Autoimmune hepatitis  |2 nationallicence 
690 7 |a BMI : Body mass index  |2 nationallicence 
690 7 |a CLD : Chronic liver disease  |2 nationallicence 
690 7 |a CHC : Chronic hepatitis C  |2 nationallicence 
690 7 |a CHB : Chronic hepatitis B  |2 nationallicence 
690 7 |a CI : Confidence interval  |2 nationallicence 
690 7 |a CT : Computed tomography  |2 nationallicence 
690 7 |a DOR : Diagnostic odds ratio  |2 nationallicence 
690 7 |a ECM : Extracellular matrix  |2 nationallicence 
690 7 |a FP : False positive  |2 nationallicence 
690 7 |a FN : False negative  |2 nationallicence 
690 7 |a HIV : Human immunodeficiency virus  |2 nationallicence 
690 7 |a HCV : Hepatitis C virus  |2 nationallicence 
690 7 |a kPa : kilopascal  |2 nationallicence 
690 7 |a LR+ : Positive likelihood ratio  |2 nationallicence 
690 7 |a LR− : Negative likelihood ratio  |2 nationallicence 
690 7 |a MRE : Magnetic resonance elastography  |2 nationallicence 
690 7 |a NPV : Negative predictive value  |2 nationallicence 
690 7 |a NAFLD : Non-alcoholic fatty liver disease  |2 nationallicence 
690 7 |a NASH : Non-alcoholic steatohepatitis  |2 nationallicence 
690 7 |a PPV : Positive predictive value  |2 nationallicence 
690 7 |a PBC : Primary biliary cirrhosis  |2 nationallicence 
690 7 |a PSC : Primary sclerosing cholangitis  |2 nationallicence 
690 7 |a ROC : Receiver operating characteristics  |2 nationallicence 
690 7 |a Se : Sensitivity  |2 nationallicence 
690 7 |a Sp : Specificity  |2 nationallicence 
690 7 |a TE : Transient elastography  |2 nationallicence 
690 7 |a TP : True positive  |2 nationallicence 
690 7 |a TN : True negative  |2 nationallicence 
690 7 |a US : Ultrasound  |2 nationallicence 
700 1 |a Guo  |D Yang  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
700 1 |a Parthasarathy  |D Sudharshan  |u Chicago Medical School, Rosalind Franklin University of Medicine, Chicago, IL, USA  |4 aut 
700 1 |a Goyal  |D Preeya  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
700 1 |a McCarthy  |D Robert  |u Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA  |4 aut 
700 1 |a Larson  |D Andrew  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
700 1 |a Miller  |D Frank  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/4(2015-04-01), 818-834  |x 0942-8925  |q 40:4<818  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-014-0137-6  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-014-0137-6  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Guo  |D Yang  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Parthasarathy  |D Sudharshan  |u Chicago Medical School, Rosalind Franklin University of Medicine, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Goyal  |D Preeya  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a McCarthy  |D Robert  |u Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Larson  |D Andrew  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Miller  |D Frank  |u Department of Radiology, Northwestern University Feinberg School of Medicine, NMH/Arkes Family Pavilion Suite 800, 676N Saint Clair, 60611, Chicago, IL, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/4(2015-04-01), 818-834  |x 0942-8925  |q 40:4<818  |1 2015  |2 40  |o 261