T1-hyperintense renal lesions: can high signal predict lack of enhancement?
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| 003 | CHVBK | ||
| 005 | 20210128100525.0 | ||
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| 008 | 210128e20151001xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00261-015-0539-0 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0539-0 | ||
| 245 | 0 | 0 | |a T1-hyperintense renal lesions: can high signal predict lack of enhancement? |h [Elektronische Daten] |c [Jenna Le, Milana Flusberg, Alla Rozenblit, Victoria Chernyak] |
| 520 | 3 | |a Objective: To establish highly specific criteria for predicting non-enhancement in T1-hyperintense non-fat-containing (T1-high) renal lesions using unenhanced fat-suppressed T1-weighted (T1-FS) images. Materials and methods: This IRB-approved, HIPAA-compliant, retrospective study included T1-high renal lesions found between 7/1/2012 and 7/1/2014. The largest lesion diameter and heterogeneity, mean signal intensity of lesion, and adjacent renal cortex were recorded from T1-FS images. The presence/absence of lesion enhancement was determined from subtraction images. T1 signal ratio (T1-SR) was calculated as (mean SI of lesion)/(mean SI of cortex). Logistic regression with binary outcome of the presence or absence of lesion enhancement was performed. Cut-off T1-SR to maximize specificity was established from receiver operator curve analysis. Results: There were 101 patients (58 [57.4%] male) with non-enhancing lesions and 80 patients (51 [63.8%] male) with enhancing lesions, mean ages 64.0±13.3 and 62.1±13.8years, respectively. Median sizes were 11mm (IQR 8-16) and 20.5mm (IQR 15-29) for non-enhancing and enhancing lesions, respectively (p<0.0001). 19/101 (18.8%) of non-enhancing and 56/80 (70.0%) of enhancing lesions were heterogeneous (p<0.0001). T1-SR was 1.77±0.6 and 1.25±0.42 for non-enhancing and enhancing lesions, respectively (p<0.0001). For each increase of 0.5 in T1-SR, odds ratio for non-enhancement was 3.3 (95% CI 1.85-5.79), adjusted for lesion size and heterogeneity. T1-SR alone had area under the curve of 0.88 (95% CI 0.78-10.89) for non-enhancement. T1-SR ≥2.15 had positive likelihood ratio of 9.5 for non-enhancement. Conclusion: Signal ratio of lesion to cortex ≥2.15 on unenhanced T1-weighted images is a highly specific predictor for non-enhancement. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Renal masses |2 nationallicence | |
| 690 | 7 | |a Renal cell carcinoma |2 nationallicence | |
| 690 | 7 | |a Renal cysts |2 nationallicence | |
| 690 | 7 | |a Incidentalomas |2 nationallicence | |
| 700 | 1 | |a Le |D Jenna |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Flusberg |D Milana |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Rozenblit |D Alla |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | |
| 700 | 1 | |a Chernyak |D Victoria |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3175-3181 |x 0942-8925 |q 40:8<3175 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0539-0 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0539-0 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Le |D Jenna |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Flusberg |D Milana |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Rozenblit |D Alla |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chernyak |D Victoria |u Department of Radiology, Montefiore Medical Center, 111 E. 210th St., 10467, Bronx, NY, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3175-3181 |x 0942-8925 |q 40:8<3175 |1 2015 |2 40 |o 261 | ||