CT sensitivity for adrenal adenoma according to lesion size

Verfasser / Beitragende:
[Sung Park, Byung Park, Jung Park, Chan Kim]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/8(2015-10-01), 3152-3160
Format:
Artikel (online)
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024 7 0 |a 10.1007/s00261-015-0521-x  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-015-0521-x 
245 0 0 |a CT sensitivity for adrenal adenoma according to lesion size  |h [Elektronische Daten]  |c [Sung Park, Byung Park, Jung Park, Chan Kim] 
520 3 |a Purpose: To retrospectively evaluate CT sensitivity for characterizing adrenal adenoma according to lesion size. Materials and methods: Between January 2004 and November 2012, 140 patients with 140 histologically proven adenomas underwent preoperative adrenal CT protocols consisting of unenhanced CT, early enhanced CT, and delayed enhanced CT. Adenomas were divided into three size groups: small adenoma (n=60), ≥1 to <2cm; medium adenoma (n=47), ≥2 to <3cm; and large adenoma (n=33), ≥3cm. Adenoma was diagnosed when a lesion met one of the following criteria: (a) unenhanced CT attenuation value ≤10 HU, (b) absolute percentage washout ≥60%, or (c) relative percentage washout ≥40%. The standard reference was pathologic examination of an adrenalectomy specimen. Adenoma size, lesion attenuation value, or percentage washout was correlated with the Spearman's rank correlation. CT sensitivities were compared between size groups of adenomas with the Fisher's exact test. Results: As adenoma size increased, the lesion attenuation value (ρ=0.324; P=0.001) increased on unenhanced CT, and the absolute (ρ=−0.186; P=0.028) or relative (ρ=−0.374; P<0.001) percentage washout decreased on early and delayed enhanced CT. CT sensitivities were 100% (60/60) for small adenomas, 97.9% (46/47) for medium adenomas, and 66.7% (22/33) for large adenomas (P<0.001). Conclusions: Adrenal CT protocols misdiagnose a substantial number of large adenomas as non-adenomas because CT sensitivity for adenoma markedly decreases, when the lesion size is 3cm or larger. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Adrenal adenoma  |2 nationallicence 
690 7 |a Computed tomography  |2 nationallicence 
690 7 |a Sensitivity  |2 nationallicence 
690 7 |a Adenoma size  |2 nationallicence 
700 1 |a Park  |D Sung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Park  |D Byung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Park  |D Jung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
700 1 |a Kim  |D Chan  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3152-3160  |x 0942-8925  |q 40:8<3152  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-015-0521-x  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-015-0521-x  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Sung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Byung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Park  |D Jung  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D Chan  |u The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3152-3160  |x 0942-8925  |q 40:8<3152  |1 2015  |2 40  |o 261