caa a22 4500 605494444 CHVBK 20210128100526.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00261-015-0521-x doi (NATIONALLICENCE)springer-10.1007/s00261-015-0521-x CT sensitivity for adrenal adenoma according to lesion size [Elektronische Daten] [Sung Park, Byung Park, Jung Park, Chan Kim] Purpose: To retrospectively evaluate CT sensitivity for characterizing adrenal adenoma according to lesion size. Materials and methods: Between January 2004 and November 2012, 140 patients with 140 histologically proven adenomas underwent preoperative adrenal CT protocols consisting of unenhanced CT, early enhanced CT, and delayed enhanced CT. Adenomas were divided into three size groups: small adenoma (n=60), ≥1 to <2cm; medium adenoma (n=47), ≥2 to <3cm; and large adenoma (n=33), ≥3cm. Adenoma was diagnosed when a lesion met one of the following criteria: (a) unenhanced CT attenuation value ≤10 HU, (b) absolute percentage washout ≥60%, or (c) relative percentage washout ≥40%. The standard reference was pathologic examination of an adrenalectomy specimen. Adenoma size, lesion attenuation value, or percentage washout was correlated with the Spearman's rank correlation. CT sensitivities were compared between size groups of adenomas with the Fisher's exact test. Results: As adenoma size increased, the lesion attenuation value (ρ=0.324; P=0.001) increased on unenhanced CT, and the absolute (ρ=−0.186; P=0.028) or relative (ρ=−0.374; P<0.001) percentage washout decreased on early and delayed enhanced CT. CT sensitivities were 100% (60/60) for small adenomas, 97.9% (46/47) for medium adenomas, and 66.7% (22/33) for large adenomas (P<0.001). Conclusions: Adrenal CT protocols misdiagnose a substantial number of large adenomas as non-adenomas because CT sensitivity for adenoma markedly decreases, when the lesion size is 3cm or larger. Springer Science+Business Media New York, 2015 Adrenal adenoma nationallicence Computed tomography nationallicence Sensitivity nationallicence Adenoma size nationallicence Park Sung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Park Byung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Park Jung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Kim Chan The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut Abdominal Imaging Springer US; http://www.springer-ny.com 40/8(2015-10-01), 3152-3160 0942-8925 40:8<3152 2015 40 261 https://doi.org/10.1007/s00261-015-0521-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00261-015-0521-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Park Sung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Park Byung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Park Jung The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 700 1- Kim Chan The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Kangnam-ku, 135-710, Seoul, Korea aut NATIONALLICENCE 773 0- Abdominal Imaging Springer US; http://www.springer-ny.com 40/8(2015-10-01), 3152-3160 0942-8925 40:8<3152 2015 40 261