Accurate estimate of pancreatic T2* values: how to deal with fat infiltration
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| 003 | CHVBK | ||
| 005 | 20210128100526.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20151001xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00261-015-0522-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00261-015-0522-9 | ||
| 245 | 0 | 0 | |a Accurate estimate of pancreatic T2* values: how to deal with fat infiltration |h [Elektronische Daten] |c [Antonella Meloni, Daniele De Marchi, Vincenzo Positano, Maria Neri, Maurizio Mangione, Petra Keilberg, Maddalena Lendini, Carla Cirotto, Alessia Pepe] |
| 520 | 3 | |a Purpose: We examined different approaches aimed to deal with the signal fluctuation of pancreatic T2* values due to fat infiltration in order to obtain accurate estimates of iron overload. Methods: Pancreatic T2* values were assessed in 20 patients (13 females, 37.24±9.12years) enrolled in the Myocardial Iron Overload in Thalassemia network without and with the application of fat suppression-FS (T2*-NoFS and T2*-FS). T2* values were assessed in three different ways: (1) from the immediate fit (original T2*); (2) discarding the echoes until the achievement of a good visual concordance between the signal and the model (final_vis T2*); (3) eliminating the echoes until the achievement of a fitting error (known)<5% (final_thres T2*). Results: For the T2*-NoFS sequence the original T2* values were significantly higher than the final_vis T2* values (difference:4.8±6.1ms; P<0.0001) and the final_thres T2* values (difference:4.3±6.1ms; P=0.006). For the T2*-FS sequence the original T2* values were comparable to final_vis and final_thres T2* values. The original T2*-FS values were significantly different from the original T2*-NoFS values. The final_vis T2*-FS values were comparable to the final_vis T2*-NoFS values and the final_thresh T2*-FS values were comparable to the final_thresh T2*-NoFS values. For both T2*-FS and T2*-NoFS sequences, the final_thres T2* values were not significantly different from the final_vis T2* values and no bias was present. Conclusions: In the clinical practice, an accurate pancreatic iron overload assessment should be done by applying FS and, when needed, by discarding the TEs until the fitting error goes below 5%. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Magnetic resonance imaging |2 nationallicence | |
| 690 | 7 | |a Pancreas T2* |2 nationallicence | |
| 690 | 7 | |a Iron overload |2 nationallicence | |
| 690 | 7 | |a Fat suppression |2 nationallicence | |
| 700 | 1 | |a Meloni |D Antonella |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a De Marchi |D Daniele |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Positano |D Vincenzo |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Neri |D Maria |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Mangione |D Maurizio |u U.O.S. Sistemi Informatici, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy |4 aut | |
| 700 | 1 | |a Keilberg |D Petra |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 700 | 1 | |a Lendini |D Maddalena |u Centro Trasfusionale, Osp. Giovanni Paolo II, Olbia, Italy |4 aut | |
| 700 | 1 | |a Cirotto |D Carla |u Servizio Trasfusionale, Azienda USL n° 1, Sassari, Italy |4 aut | |
| 700 | 1 | |a Pepe |D Alessia |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | |
| 773 | 0 | |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3129-3136 |x 0942-8925 |q 40:8<3129 |1 2015 |2 40 |o 261 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00261-015-0522-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00261-015-0522-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Meloni |D Antonella |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a De Marchi |D Daniele |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Positano |D Vincenzo |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Neri |D Maria |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mangione |D Maurizio |u U.O.S. Sistemi Informatici, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Keilberg |D Petra |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lendini |D Maddalena |u Centro Trasfusionale, Osp. Giovanni Paolo II, Olbia, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cirotto |D Carla |u Servizio Trasfusionale, Azienda USL n° 1, Sassari, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Pepe |D Alessia |u CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Area della Ricerca S. Cataldo, Via Moruzzi, 1, 56124, Pisa, Italy |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Abdominal Imaging |d Springer US; http://www.springer-ny.com |g 40/8(2015-10-01), 3129-3136 |x 0942-8925 |q 40:8<3129 |1 2015 |2 40 |o 261 | ||