Spectrum of IgG4-related disease on multi-detector CT: a 5-year study of a single medical center data

Verfasser / Beitragende:
[Yonglan He, Xuechao Du, Ning Ding, Zhuo Li, Weixun Zhou, Bo Chen, Zhengyu Jin, Hao Sun, Liang Zhu, Huadan Xue]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/8(2015-10-01), 3104-3116
Format:
Artikel (online)
ID: 605494606
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024 7 0 |a 10.1007/s00261-015-0527-4  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s00261-015-0527-4 
245 0 0 |a Spectrum of IgG4-related disease on multi-detector CT: a 5-year study of a single medical center data  |h [Elektronische Daten]  |c [Yonglan He, Xuechao Du, Ning Ding, Zhuo Li, Weixun Zhou, Bo Chen, Zhengyu Jin, Hao Sun, Liang Zhu, Huadan Xue] 
520 3 |a Purpose: To discuss the diverse imaging features of pancreatic and extra-pancreatic lesions of IgG4-related disease (IgG4-RD) on multi-detector CT (MDCT). Methods: This retrospective study was approved by our institutional research ethics board, and informed consent was waived. From 2008 to 2013, 159 patients including 120 men (mean age 57years; range 27-79years) and 39 women (mean age 51years; range 25-83years) who met the comprehensive diagnostic criteria for IgG4-RD (2011) were enrolled. MDCT images consisted of 153 abdominal images, 64 pelvic images, 64 thoracic images, and 8 neck images were retrospectively analyzed in consensus by two radiologists with expertise in the CT diagnosis of IgG4-RD. Results: Only 11 (11/153, 7.2%) IgG4-RD patients had been found with no pancreatic involvement. 145 (145/159, 91.2%) patients had various extra-pancreatic lesions, including involvement of biliary tree (93/153, 60.8%), peri-pancreatic vessels (66/153, 43.1%), IgG4-related lymphadenopathy, peri-abdominal aorta arteritis or retroperitoneal fibrosis, head and neck lesions, etc. Renal lesions were found in 26 (26/153, 17.0%) IgG4-RD patients with 4 types of renal parenchymal involvement. Lung lesions were found in 44 (44/64, 68.7%) IgG4-RD patients, which were classified into 7 types. Conclusions: Pancreatic and various extra-pancreatic lesions may be involved in IgG4-RD patients frequently with typical imaging findings. It is useful to recognize the atypical or uncommon imaging features to help the diagnosis of IgG4-RD together with other serologic or histopathologic findings. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a IgG4-related disease  |2 nationallicence 
690 7 |a Multi-detector CT  |2 nationallicence 
690 7 |a Pancreatic lesions  |2 nationallicence 
690 7 |a Extra-pancreatic lesions  |2 nationallicence 
700 1 |a He  |D Yonglan  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Du  |D Xuechao  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Ding  |D Ning  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Li  |D Zhuo  |u Amcare Clinic, Beijing, People's Republic of China  |4 aut 
700 1 |a Zhou  |D Weixun  |u Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China  |4 aut 
700 1 |a Chen  |D Bo  |u Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China  |4 aut 
700 1 |a Jin  |D Zhengyu  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Sun  |D Hao  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Zhu  |D Liang  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
700 1 |a Xue  |D Huadan  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3104-3116  |x 0942-8925  |q 40:8<3104  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-015-0527-4  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-015-0527-4  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a He  |D Yonglan  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Du  |D Xuechao  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ding  |D Ning  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Li  |D Zhuo  |u Amcare Clinic, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhou  |D Weixun  |u Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chen  |D Bo  |u Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Jin  |D Zhengyu  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sun  |D Hao  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhu  |D Liang  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Xue  |D Huadan  |u Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Shuai Fu Yuan #1, Dongcheng Dist., 100730, Beijing, People's Republic of China  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3104-3116  |x 0942-8925  |q 40:8<3104  |1 2015  |2 40  |o 261