Amyloidosis of the liver on shear wave elastography: case report and review of literature

Verfasser / Beitragende:
[Dmitry Trifanov, Manish Dhyani, Jacob Bledsoe, Joseph Misdraji, Atul Bhan, Raymond Chung, Anthony Samir]
Ort, Verlag, Jahr:
2015
Enthalten in:
Abdominal Imaging, 40/8(2015-10-01), 3078-3083
Format:
Artikel (online)
ID: 605494649
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024 7 0 |a 10.1007/s00261-015-0519-4  |2 doi 
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245 0 0 |a Amyloidosis of the liver on shear wave elastography: case report and review of literature  |h [Elektronische Daten]  |c [Dmitry Trifanov, Manish Dhyani, Jacob Bledsoe, Joseph Misdraji, Atul Bhan, Raymond Chung, Anthony Samir] 
520 3 |a Amyloidosis is extremely rare, with an estimated 2225 new US cases reported annually. Signs and symptoms of the disease are subtle and imaging findings are not pathognomonic. Currently, diagnosis requires biopsy to demonstrate the deposition of amyloid. Elastography is a new imaging modality that evaluates tissue elasticity. It has shown to have efficacy in characterizing thyroid nodules, detecting prostate cancer, and staging liver fibrosis. We present a case of hepatic amyloidosis in a 51-year-old male that demonstrates significantly increased stiffness with a median value of 99.1kPa (range 25.7-188.9kPa) on shear-wave elastography (SWE) imaging, which is significantly higher than thecut-off range reported for cirrhosis on SWE (10.4-11.5kPa). This finding raises the possibility that elastographic imaging may be sensitive to tissue mechanical changes induced by amyloid deposition. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Amyloidosis  |2 nationallicence 
690 7 |a Elastography  |2 nationallicence 
690 7 |a Liver fibrosis  |2 nationallicence 
690 7 |a Liver biopsy  |2 nationallicence 
690 7 |a SWE  |2 nationallicence 
690 7 |a Ultrasound elastography  |2 nationallicence 
700 1 |a Trifanov  |D Dmitry  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
700 1 |a Dhyani  |D Manish  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
700 1 |a Bledsoe  |D Jacob  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
700 1 |a Misdraji  |D Joseph  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
700 1 |a Bhan  |D Atul  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
700 1 |a Chung  |D Raymond  |u Department of Hepatology, Medicine, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
700 1 |a Samir  |D Anthony  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
773 0 |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3078-3083  |x 0942-8925  |q 40:8<3078  |1 2015  |2 40  |o 261 
856 4 0 |u https://doi.org/10.1007/s00261-015-0519-4  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s00261-015-0519-4  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Trifanov  |D Dmitry  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Dhyani  |D Manish  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bledsoe  |D Jacob  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Misdraji  |D Joseph  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bhan  |D Atul  |u Department of Pathology, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chung  |D Raymond  |u Department of Hepatology, Medicine, Massachusetts General Hospital [MGH], Harvard Medical School, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Samir  |D Anthony  |u Department of Abdominal Imaging and Intervention, Massachusetts General Hospital [MGH], Harvard Medical School, 55 Fruit Street, 02114, Boston, MA, USA  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Abdominal Imaging  |d Springer US; http://www.springer-ny.com  |g 40/8(2015-10-01), 3078-3083  |x 0942-8925  |q 40:8<3078  |1 2015  |2 40  |o 261